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- Document type:
- Zeitschriftenaufsatz
- Author(s):
- Boettler, Ute; Volz, Nadine; Pahlke, Gudrun; Teller, Nicole; Kotyczka, Christine; Somoza, Veronika; Stiebitz, Herbert; Bytof, Gerhard; Lantz, Ingo; Lang, Roman; Hofmann, Thomas; Marko, Doris
- Title:
- Coffees rich in chlorogenic acid or N-methylpyridinium induce chemopreventive phase II-enzymes via the Nrf2/ARE pathway in vitro and in vivo
- Abstract:
- Recently, the coffee constituents 5-O-caffeoylquinic acid (CGA) and N-methylpyridinium (NMP) were identified as inducers of the Nrf2/antioxidant-response element (ARE) detoxifying pathway under cell-culture condition. To study the impact of CGA and NMP on the Nrf2-activating properties of a complex coffee beverage, two different model coffees were generated by variation of the roasting conditions: a low-roast coffee rich in CGA and a heavy-roast low in CGA but containing high levels of NMP. Acti... »
- Journal title:
- Molecular nutrition & Food research
- Year:
- 2011
- Journal volume:
- 55
- Journal issue:
- 5
- Pages contribution:
- 798--802
- Fulltext / DOI:
- doi:10.1002/mnfr.201100115
- Print-ISSN:
- 1613-4125
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