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Titel:

Coffees rich in chlorogenic acid or N-methylpyridinium induce chemopreventive phase II-enzymes via the Nrf2/ARE pathway in vitro and in vivo

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Boettler, Ute; Volz, Nadine; Pahlke, Gudrun; Teller, Nicole; Kotyczka, Christine; Somoza, Veronika; Stiebitz, Herbert; Bytof, Gerhard; Lantz, Ingo; Lang, Roman; Hofmann, Thomas; Marko, Doris
Abstract:
Recently, the coffee constituents 5-O-caffeoylquinic acid (CGA) and N-methylpyridinium (NMP) were identified as inducers of the Nrf2/antioxidant-response element (ARE) detoxifying pathway under cell-culture condition. To study the impact of CGA and NMP on the Nrf2-activating properties of a complex coffee beverage, two different model coffees were generated by variation of the roasting conditions: a low-roast coffee rich in CGA and a heavy-roast low in CGA but containing high levels of NMP. Acti...     »
Zeitschriftentitel:
Molecular nutrition & Food research
Jahr:
2011
Band / Volume:
55
Heft / Issue:
5
Seitenangaben Beitrag:
798--802
Volltext / DOI:
doi:10.1002/mnfr.201100115
Print-ISSN:
1613-4125
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