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Macrophage migration inhibitory factor (MIF) and its homolog D-dopachrome tautomerase (D-DT) are significant promotors of UVB- but not chemically induced non-melanoma skin cancer
Scientific Reports
2023
13
1

Krammer, Christine;Yang, Bishan;Reichl, Sabrina;Besson‐Girard, Simon;Ji, Hao;Bolini, Verena;Schulte, Corinna;Noels, Heidi;Schlepckow, Kai;Jocher, Georg;Werner, Georg;Willem, Michael;El Bounkari, Omar;Kapurniotu, Aphrodite;Gokce, Ozgun;Weber, Christian;Mohanta, Sarajo;Bernhagen, Jürgen
Pathways linking aging and atheroprotection in Mif ‐deficient atherosclerotic mice
The FASEB Journal
2023
37
3

Kapurniotu, Aphrodite;Bernhagen, Jürgen
Lasso-grafted designer cytokines
Nature Biomedical Engineering
2022

Brandhofer, Markus;Hoffmann, Adrian;Blanchet, Xavier;Siminkovitch, Elena;Rohlfing, Anne-Katrin;El Bounkari, Omar;Nestele, Jeremy A.;Bild, Alexander;Kontos, Christos;Hille, Kathleen;Rohde, Vanessa;Fröhlich, Adrian;Golemi, Jona;Gokce, Ozgun;Krammer, Christine;Scheiermann, Patrick;Tsilimparis, Nikolaos;Sachs, Nadja;Kempf, Wolfgang E.;Maegdefessel, Lars;Otabil, Michael K.;Megens, Remco T. A.;Ippel, Hans;Koenen, Rory R.;Luo, Junfu;Engelmann, Bernd;Mayo, Kevin H.;Gawaz, Meinrad;Kapurniotu, Aphrodite;Weber, Christian;von Hundelshausen, Philipp;Bernhagen, Jürgen
Heterocomplexes between the atypical chemokine MIF and the CXC-motif chemokine CXCL4L1 regulate inflammation and thrombus formation
Cellular and Molecular Life Sciences
2022
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Taş, Karin;Volta, Beatrice Dalla;Lindner, Christina;El Bounkari, Omar;Hille, Kathleen;Tian, Yuan;Puig-Bosch, Xènia;Ballmann, Markus;Hornung, Simon;Ortner, Martin;Prem, Sophia;Meier, Laura;Rammes, Gerhard;Haslbeck, Martin;Weber, Christian;Megens, Remco T. A.;Bernhagen, Jürgen;Kapurniotu, Aphrodite
Designed peptides as nanomolar cross-amyloid inhibitors acting via supramolecular nanofiber co-assembly
Nature Communications
2022
13
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Kontos, Christos;El Bounkari, Omar;Krammer, Christine;Sinitski, Dzmitry;Hille, Kathleen;Zan, Chunfang;Yan, Guangyao;Wang, Sijia;Gao, Ying;Brandhofer, Markus;Megens, Remco T. A.;Hoffmann, Adrian;Pauli, Jessica;Asare, Yaw;Gerra, Simona;Bourilhon, Priscila;Leng, Lin;Eckstein, Hans-Henning;Kempf, Wolfgang E.;Pelisek, Jaroslav;Gokce, Ozgun;Maegdefessel, Lars;Bucala, Richard;Dichgans, Martin;Weber, Christian;Kapurniotu, Aphrodite;Bernhagen, Jürgen
Designed CXCR4 mimic acts as a soluble chemokine receptor that blocks atherogenic inflammation by agonist-specific targeting
Nature Communications
2020
11
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Krammer, Christine;Kontos, Christos;Dewor, Manfred;Hille, Kathleen;Dalla Volta, Beatrice;El Bounkari, Omar;Taş, Karin;Sinitski, Dzmitry;Brandhofer, Markus;Megens, Remco T.A.;Weber, Christian;Schultz, Joshua R;Bernhagen, Jürgen;Kapurniotu, Aphrodite
A MIF‐derived cyclopeptide that inhibits MIF binding and atherogenic signaling via the chemokine receptor CXCR2
ChemBioChem
2020

Kapurniotu, Aphrodite
Enlightening amyloid fibrils linked to type 2 diabetes and cross-interactions with Aβ
Nature Structural & Molecular Biology
2020
27
11
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Spanopoulou, Anna;Heidrich, Luzia;Chen, Hong-Ru;Frost, Christina;Hrle, Dean;Malideli, Eleni;Hille, Kathleen;Grammatikopoulos, Alexandros;Bernhagen, Jürgen;Zacharias, Martin;Rammes, Gerhard;Kapurniotu, Aphrodite
Designed Macrocyclic Peptides as Nanomolar Amyloid Inhibitors Based on Minimal Recognition Elements
Angewandte Chemie International Edition
2018
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Sinitski, Dzmitry;Kontos, Christos;Krammer, Christine;Asare, Yaw;Kapurniotu, Aphrodite;Bernhagen, Jürgen
Macrophage Migration Inhibitory Factor (MIF)-Based Therapeutic Concepts in Atherosclerosis and Inflammation
Thrombosis and Haemostasis
2019
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04
553-566