El Bounkari, Omar;Zan, Chunfang;Yang, Bishan;Ebert, Simon;Wagner, Jonas;Bugar, Elina;Kramer, Naomi;Bourilhon, Priscila;Kontos, Christos;Zarwel, Marlies;Sinitski, Dzmitry;Milic, Jelena;Jansen, Yvonne;Kempf, Wolfgang E.;Sachs, Nadja;Maegdefessel, Lars;Ji, Hao;Gokce, Ozgun;Riols, Fabien;Haid, Mark;Gerra, Simona;Hoffmann, Adrian;Brandhofer, Markus;Avdic, Maida;Bucala, Richard;Megens, Remco T. A.;Willemsen, Nienke;Messerer, Denise;Schulz, Christian;Bartelt, Alexander;Harm, Tobias;Rath, Dominik;Döring, Yvonne;Gawaz, Meinrad;Weber, Christian;Kapurniotu, Aphrodite;Bernhagen, Jürgen
An atypical atherogenic chemokine that promotes advanced atherosclerosis and hepatic lipogenesis
Nature Communications
2025
16
1

Hornung, Simon;Vogl, Dominik P.;Naltsas, Denise;Volta, Beatrice Dalla;Ballmann, Markus;Marcon, Beatrice;Syed, Muhammed Muazzam Kamil;Wu, Yiyang;Spanopoulou, Anna;Feederle, Regina;Heidrich, Luzia;Bernhagen, Jürgen;Koeglsperger, Thomas;Höglinger, Günter U.;Rammes, Gerhard;Lashuel, Hilal A.;Kapurniotu, Aphrodite
Multi‐Targeting Macrocyclic Peptides as Nanomolar Inhibitors of Self‐ and Cross‐Seeded Amyloid Self‐Assembly of α‐Synuclein
Angewandte Chemie International Edition
2025
64
14

Rodina, Natalia;Hornung, Simon;Sarkar, Riddhiman;Suladze, Saba;Peters, Carsten;Schmid, Philipp W. N.;Niu, Zheng;Haslbeck, Martin;Buchner, Johannes;Kapurniotu, Aphrodite;Reif, Bernd
Modulation of Alzheimer’s Disease Aβ40 Fibril Polymorphism by the Small Heat Shock Protein αB-Crystallin
Journal of the American Chemical Society
2024
146
28
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Huth, Sebastian;Huth, Laura;Heise, Ruth;Marquardt, Yvonne;Lopopolo, Linda;Piecychna, Marta;Boor, Peter;Fingerle-Rowson, Günter;Kapurniotu, Aphrodite;Yazdi, Amir S.;Bucala, Richard;Bernhagen, Jürgen;Baron, Jens Malte
Macrophage migration inhibitory factor (MIF) and its homolog D-dopachrome tautomerase (D-DT) are significant promotors of UVB- but not chemically induced non-melanoma skin cancer
Scientific Reports
2023
13
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Krammer, Christine;Yang, Bishan;Reichl, Sabrina;Besson‐Girard, Simon;Ji, Hao;Bolini, Verena;Schulte, Corinna;Noels, Heidi;Schlepckow, Kai;Jocher, Georg;Werner, Georg;Willem, Michael;El Bounkari, Omar;Kapurniotu, Aphrodite;Gokce, Ozgun;Weber, Christian;Mohanta, Sarajo;Bernhagen, Jürgen
Pathways linking aging and atheroprotection in Mif ‐deficient atherosclerotic mice
The FASEB Journal
2023
37
3

Kapurniotu, Aphrodite;Bernhagen, Jürgen
Lasso-grafted designer cytokines
Nature Biomedical Engineering
2022

Brandhofer, Markus;Hoffmann, Adrian;Blanchet, Xavier;Siminkovitch, Elena;Rohlfing, Anne-Katrin;El Bounkari, Omar;Nestele, Jeremy A.;Bild, Alexander;Kontos, Christos;Hille, Kathleen;Rohde, Vanessa;Fröhlich, Adrian;Golemi, Jona;Gokce, Ozgun;Krammer, Christine;Scheiermann, Patrick;Tsilimparis, Nikolaos;Sachs, Nadja;Kempf, Wolfgang E.;Maegdefessel, Lars;Otabil, Michael K.;Megens, Remco T. A.;Ippel, Hans;Koenen, Rory R.;Luo, Junfu;Engelmann, Bernd;Mayo, Kevin H.;Gawaz, Meinrad;Kapurniotu, Aphrodite;Weber, Christian;von Hundelshausen, Philipp;Bernhagen, Jürgen
Heterocomplexes between the atypical chemokine MIF and the CXC-motif chemokine CXCL4L1 regulate inflammation and thrombus formation
Cellular and Molecular Life Sciences
2022
79
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Taş, Karin;Volta, Beatrice Dalla;Lindner, Christina;El Bounkari, Omar;Hille, Kathleen;Tian, Yuan;Puig-Bosch, Xènia;Ballmann, Markus;Hornung, Simon;Ortner, Martin;Prem, Sophia;Meier, Laura;Rammes, Gerhard;Haslbeck, Martin;Weber, Christian;Megens, Remco T. A.;Bernhagen, Jürgen;Kapurniotu, Aphrodite
Designed peptides as nanomolar cross-amyloid inhibitors acting via supramolecular nanofiber co-assembly
Nature Communications
2022
13
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Kontos, Christos;El Bounkari, Omar;Krammer, Christine;Sinitski, Dzmitry;Hille, Kathleen;Zan, Chunfang;Yan, Guangyao;Wang, Sijia;Gao, Ying;Brandhofer, Markus;Megens, Remco T. A.;Hoffmann, Adrian;Pauli, Jessica;Asare, Yaw;Gerra, Simona;Bourilhon, Priscila;Leng, Lin;Eckstein, Hans-Henning;Kempf, Wolfgang E.;Pelisek, Jaroslav;Gokce, Ozgun;Maegdefessel, Lars;Bucala, Richard;Dichgans, Martin;Weber, Christian;Kapurniotu, Aphrodite;Bernhagen, Jürgen
Designed CXCR4 mimic acts as a soluble chemokine receptor that blocks atherogenic inflammation by agonist-specific targeting
Nature Communications
2020
11
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Krammer, Christine;Kontos, Christos;Dewor, Manfred;Hille, Kathleen;Dalla Volta, Beatrice;El Bounkari, Omar;Taş, Karin;Sinitski, Dzmitry;Brandhofer, Markus;Megens, Remco T.A.;Weber, Christian;Schultz, Joshua R;Bernhagen, Jürgen;Kapurniotu, Aphrodite
A MIF‐derived cyclopeptide that inhibits MIF binding and atherogenic signaling via the chemokine receptor CXCR2
ChemBioChem
2020