Zachmann, M.;Mathias, G.;Antes, I.
Parameterization of the Hamiltonian Dielectric Solvent (HADES) Reaction-Field Method for the Solvation Free Energies of Amino Acid Side-Chain Analogs
Chemphyschem
2015
16
8
1739-49

Yamane, D.;McGivern, D. R.;Wauthier, E.;Yi, M.;Madden, V. J.;Welsch, C.;Antes, I.;Wen, Y.;Chugh, P. E.;McGee, C. E.;Widman, D. G.;Misumi, I.;Bandyopadhyay, S.;Kim, S.;Shimakami, T.;Oikawa, T.;Whitmire, J. K.;Heise, M. T.;Dittmer, D. P.;Kao, C. C.;Pitson, S. M.;Merrill, A. H., Jr.;Reid, L. M.;Lemon, S. M.
Regulation of the hepatitis C virus RNA replicase by endogenous lipid peroxidation
Nat Med
2014
20
8
927-35

Welsch, C.;Schweizer, S.;Shimakami, T.;Domingues, F. S.;Kim, S.;Lemon, S. M.;Antes, I.
Ketoamide resistance and hepatitis C virus fitness in val55 variants of the NS3 serine protease
Antimicrob Agents Chemother
2012
56
4
1907-15

Welsch, C.;Haselow, K.;Gouttenoire, J.;Schneider, M.;Morikawa, K.;Martinez, Y.;Susser, S.;Sarrazin, C.;Zeuzem, S.;Antes, I.;Moradpour, D.;Lange, C. M.
Hepatitis C virus variants resistant to macrocyclic NS3-4A inhibitors subvert IFN-beta induction by efficient MAVS cleavage
J Hepatol
2015
62
4
779-84

Welsch, C.;Domingues, F. S.;Susser, S.;Antes, I.;Hartmann, C.;Mayr, G.;Schlicker, A.;Sarrazin, C.;Albrecht, M.;Zeuzem, S.;Lengauer, T.
Molecular basis of telaprevir resistance due to V36 and T54 mutations in the NS3-4A protease of the hepatitis C virus
Genome Biol
2008
9
1
R16

Welker, M. W.;Welsch, C.;Meyer, A.;Antes, I.;Albrecht, M.;Forestier, N.;Kronenberger, B.;Lengauer, T.;Piiper, A.;Zeuzem, S.;Sarrazin, C.
Dimerization of the hepatitis C virus nonstructural protein 4B depends on the integrity of an aminoterminal basic leucine zipper
Protein Sci
2010
19
7
1327-36

Voets, M.;Antes, I.;Scherer, C.;Muller-Vieira, U.;Biemel, K.;Marchais-Oberwinkler, S.;Hartmann, R. W.
Synthesis and evaluation of heteroaryl-substituted dihydronaphthalenes and indenes: potent and selective inhibitors of aldosterone synthase (CYP11B2) for the treatment of congestive heart failure and myocardial fibrosis
J Med Chem
2006
49
7
2222-31

Voets, M.;Antes, I.;Scherer, C.;Muller-Vieira, U.;Biemel, K.;Barassin, C.;Marchais-Oberwinkler, S.;Hartmann, R. W.
Heteroaryl-substituted naphthalenes and structurally modified derivatives: selective inhibitors of CYP11B2 for the treatment of congestive heart failure and myocardial fibrosis
J Med Chem
2005
48
21
6632-42

Ulmschneider, S.;Muller-Vieira, U.;Mitrenga, M.;Hartmann, R. W.;Oberwinkler-Marchais, S.;Klein, C. D.;Bureik, M.;Bernhardt, R.;Antes, I.;Lengauer, T.
Synthesis and evaluation of imidazolylmethylenetetrahydronaphthalenes and imidazolylmethyleneindanes: potent inhibitors of aldosterone synthase
J Med Chem
2005
48
6
1796-805

Ulmschneider, S.;Muller-Vieira, U.;Klein, C. D.;Antes, I.;Lengauer, T.;Hartmann, R. W.
Synthesis and evaluation of (pyridylmethylene)tetrahydronaphthalenes/-indanes and structurally modified derivatives: potent and selective inhibitors of aldosterone synthase
J Med Chem
2005
48
5
1563-75