Stelzer, Walter;Langosch, Dieter
Conformationally Flexible Sites within the Transmembrane Helices of Amyloid Precursor Protein and Notch1 Receptor
Biochemistry
2019
58
28
3065-3068

Götz, Alexander;Mylonas, Nadine;Högel, Philipp;Silber, Mara;Heinel, Hannes;Menig, Simon;Vogel, Alexander;Feyrer, Hannes;Huster, Daniel;Luy, Burkhard;Langosch, Dieter;Scharnagl, Christina;Muhle-Goll, Claudia;Kamp, Frits;Steiner, Harald
Modulating hinge flexibility in the APP transmembrane domain alters γ-secretase cleavage
Biophysical Journal
2019

Götz, Alexander;Högel, Philipp;Silber, Mara;Chaitoglou, Iro;Luy, Burkhard;Muhle-Goll, Claudia;Scharnagl, Christina;Langosch, Dieter
Increased H-Bond Stability Relates to Altered ε-Cleavage Efficiency and Aβ Levels in the I45T Familial Alzheimer’s Disease Mutant of APP
Scientific Reports
2019
9
1

Yücel, Sara Suna;Stelzer, Walter;Lorenzoni, Alessandra;Wozny, Manfred;Langosch, Dieter;Lemberg, Marius K.
The Metastable XBP1u Transmembrane Domain Defines Determinants for Intramembrane Proteolysis by Signal Peptide Peptidase
Cell Reports
2019
26
11
3087-3099.e11

Yucel, Sara Suna; Stelzer, Walter; Lorenzoni, Alessandra; Wozny, Manfred; Langosch, Dieter; Lemberg, Marius K
The metastable XBP1u transmembrane domain defines determinants for intramembrane proteolysis by signal peptide peptidase
bioRxiv
2018

Scheidt, Holger A.;Kolocaj, Katja;Veje Kristensen, Julie;Huster, Daniel;Langosch, Dieter
Transmembrane Helix Induces Membrane Fusion through Lipid Binding and Splay
The Journal of Physical Chemistry Letters
2018
9
12
3181-3186

Högel, Philipp;Götz, Alexander;Kuhne, Felix;Ebert, Maximilian;Stelzer, Walter;Rand, Kasper D.;Scharnagl, Christina;Langosch, Dieter
Glycine Perturbs Local and Global Conformational Flexibility of a Transmembrane Helix
Biochemistry
2018
57
8
1326-1337

Julius, Ayse;Laur, Lisa;Schanzenbach, Christoph;Langosch, Dieter
BLaTM 2.0, a Genetic Tool Revealing Preferred Antiparallel Interaction of Transmembrane Helix 4 of the Dual-Topology Protein EmrE
Journal of Molecular Biology
2017
429
11
1630-1637

Schanzenbach, Christoph;Schmidt, Fabian C.;Breckner, Patrick;Teese, Mark G.;Langosch, Dieter
Identifying ionic interactions within a membrane using BLaTM, a genetic tool to measure homo- and heterotypic transmembrane helix-helix interactions
Scientific Reports
2017
7
43476

Ried, Christian Lothar;Kube, Sebastian;Kirrbach, Jan;Langosch, Dieter
Homotypic Interaction and Amino Acid Distribution of Unilaterally Conserved Transmembrane Helices
Journal of Molecular Biology
2012
420
3
251-257