Spitz, Charlotte;Schlosser, Christine;Guschtschin-Schmidt, Nadja;Stelzer, Walter;Menig, Simon;Götz, Alexander;Haug-Kröper, Martina;Scharnagl, Christina;Langosch, Dieter;Muhle-Goll, Claudia;Fluhrer, Regina
Non-canonical Shedding of TNFα by SPPL2a Is Determined by the Conformational Flexibility of Its Transmembrane Helix
iScience
2020
23
12
101775

Xiao, Yao;Zeng, Bo;Berner, Nicola;Frishman, Dmitrij;Langosch, Dieter;George Teese, Mark
Experimental determination and data-driven prediction of homotypic transmembrane domain interfaces
Computational and Structural Biotechnology Journal
2020
18
3230-3242

Scheidt, Holger A.;Kolocaj, Katja;Konrad, David B.;Frank, James A.;Trauner, Dirk;Langosch, Dieter;Huster, Daniel
Light-induced lipid mixing implies a causal role of lipid splay in membrane fusion
Biochimica et Biophysica Acta (BBA) - Biomembranes
2020
183438

Heckmeier, Philipp J.;Agam, Ganesh;Teese, Mark G.;Hoyer, Maria;Stehle, Ralf;Lamb, Don C.;Langosch, Dieter
Determining the Stoichiometry of Small Protein Oligomers Using Steady-State Fluorescence Anisotropy
Biophysical Journal
2020
119
1
99-114

Stelzer, Walter;Langosch, Dieter
Conformationally Flexible Sites within the Transmembrane Helices of Amyloid Precursor Protein and Notch1 Receptor
Biochemistry
2019
58
28
3065-3068

Götz, Alexander;Mylonas, Nadine;Högel, Philipp;Silber, Mara;Heinel, Hannes;Menig, Simon;Vogel, Alexander;Feyrer, Hannes;Huster, Daniel;Luy, Burkhard;Langosch, Dieter;Scharnagl, Christina;Muhle-Goll, Claudia;Kamp, Frits;Steiner, Harald
Modulating hinge flexibility in the APP transmembrane domain alters γ-secretase cleavage
Biophysical Journal
2019

Götz, Alexander;Högel, Philipp;Silber, Mara;Chaitoglou, Iro;Luy, Burkhard;Muhle-Goll, Claudia;Scharnagl, Christina;Langosch, Dieter
Increased H-Bond Stability Relates to Altered ε-Cleavage Efficiency and Aβ Levels in the I45T Familial Alzheimer’s Disease Mutant of APP
Scientific Reports
2019
9
1

Yücel, Sara Suna;Stelzer, Walter;Lorenzoni, Alessandra;Wozny, Manfred;Langosch, Dieter;Lemberg, Marius K.
The Metastable XBP1u Transmembrane Domain Defines Determinants for Intramembrane Proteolysis by Signal Peptide Peptidase
Cell Reports
2019
26
11
3087-3099.e11

Yucel, Sara Suna; Stelzer, Walter; Lorenzoni, Alessandra; Wozny, Manfred; Langosch, Dieter; Lemberg, Marius K
The metastable XBP1u transmembrane domain defines determinants for intramembrane proteolysis by signal peptide peptidase
bioRxiv
2018

Scheidt, Holger A.;Kolocaj, Katja;Veje Kristensen, Julie;Huster, Daniel;Langosch, Dieter
Transmembrane Helix Induces Membrane Fusion through Lipid Binding and Splay
The Journal of Physical Chemistry Letters
2018
9
12
3181-3186