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Titel:

In Vitro Effect of Taraxacum officinale Leaf Aqueous Extract on the Interaction between ACE2 Cell Surface Receptor and SARS-CoV-2 Spike Protein D614 and Four Mutants

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Tran, Hoai Thi Thu; Gigl, Michael; Le, Nguyen Phan Khoi; Dawid, Corinna; Lamy, Evelyn
Abstract:
To date, there have been rapidly spreading new SARS-CoV-2 “variants of concern”. They all contain multiple mutations in the ACE2 receptor recognition site of the spike protein, compared to the original Wuhan sequence, which is of great concern, because of their potential for immune escape. Here we report on the efficacy of common dandelion (Taraxacum officinale) to block protein–protein interaction of SARS-COV-2 spike to the human ACE2 receptor. This could be shown for the wild type and mutant f...     »
Zeitschriftentitel:
Pharmaceuticals
Jahr:
2021
Band / Volume:
14
Jahr / Monat:
2021-10
Heft / Issue:
10
Volltext / DOI:
doi:10.3390/ph14101055
WWW:
https://www.mdpi.com/1424-8247/14/10/1055
Print-ISSN:
1424-8247
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