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Titel:

Chemoselective synthesis of peptides containing major advanced glycation end-products of lysine and arginine

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Gruber, P.; Hofmann, T.
Abstract:
Useful methodologies have been developed, enabling the straightforward synthesis of peptides containing N(epsilon)-(carboxymethyl)-L-lysine (CML) and N(epsilon)-(carboxyethyl)-L-lysine (CEL), the major glycation end-products of lysine. These lysine derivatives were successfully incorporated into growing peptide chains via standard Fmoc/Ot-Bu peptide synthesis procedures. For the synthesis of peptides containing major glycation end-products of arginine, synthetic routes have been developed enabli...     »
Zeitschriftentitel:
The Journal of Peptide Research : official journal of the American Peptide Society
Jahr:
2005
Band / Volume:
66
Heft / Issue:
3
Seitenangaben Beitrag:
111--124
Volltext / DOI:
doi:10.1111/j.1399-3011.2005.00279.x
Print-ISSN:
1397-002X
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