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Titel:

Multi-parametric approach to identify coffee components that regulate mechanisms of gastric acid secretion

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Rubach, Malte; Lang, Roman; Seebach, Elisabeth; Somoza, Mark M.; Hofmann, Thomas; Somoza, Veronika
Abstract:
SCOPE: Chlorogenic acid (CA), caffeine (CAFF), pyrogallol (PYR), catechol (CAT), (beta)N-alkanoyl-hydroxytryptamides (C5HT) and N-methylpyridinium (N-MP) were evaluated for their influence on mechanisms of gastric acid secretion as single compounds and in biomimetic mixtures. METHODS AND RESULTS: Compounds were tested in coffee representative concentrations. Human gastric cancer cells (HGT-1) were used to study the proton secretory activity by Ussing chamber experiments and FACS analysis. For ac...     »
Zeitschriftentitel:
Molecular nutrition & Food research
Jahr:
2012
Band / Volume:
56
Heft / Issue:
2
Seitenangaben Beitrag:
325--335
Volltext / DOI:
doi:10.1002/mnfr.201100453
Print-ISSN:
1613-4125
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