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Title:

Application of hydrophilic interaction liquid chromatography/comparative taste dilution analysis for identification of a bitter inhibitor by a combinatorial approach based on Maillard reaction chemistry

Document type:
Zeitschriftenaufsatz
Author(s):
Soldo, Tomislav; Hofmann, Thomas
Abstract:
Activity-directed fractionation of heated carbohydrate/alanine solutions recently led to the discovery of (+)-(S)-1-(1-carboxyethyl)-5-hydroxy-2-(hydroxymethyl)pyridinium inner salt (1, alapyridaine), and it has been shown that this compound lowers the detection thresholds of sugars, glutamate, and NaCl solutions, whereas no influence on bitter perception was observed. As this class of Maillard-derived pyridinium betaines seemed to be promising targets for further research on their taste modulat...     »
Journal title:
Journal of Agricultural and Food Chemistry
Year:
2005
Journal volume:
53
Journal issue:
23
Pages contribution:
9165--9171
Fulltext / DOI:
doi:10.1021/jf051701o
Print-ISSN:
0021-8561
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