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Titel:

Application of hydrophilic interaction liquid chromatography/comparative taste dilution analysis for identification of a bitter inhibitor by a combinatorial approach based on Maillard reaction chemistry

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Soldo, Tomislav; Hofmann, Thomas
Abstract:
Activity-directed fractionation of heated carbohydrate/alanine solutions recently led to the discovery of (+)-(S)-1-(1-carboxyethyl)-5-hydroxy-2-(hydroxymethyl)pyridinium inner salt (1, alapyridaine), and it has been shown that this compound lowers the detection thresholds of sugars, glutamate, and NaCl solutions, whereas no influence on bitter perception was observed. As this class of Maillard-derived pyridinium betaines seemed to be promising targets for further research on their taste modulat...     »
Zeitschriftentitel:
Journal of Agricultural and Food Chemistry
Jahr:
2005
Band / Volume:
53
Heft / Issue:
23
Seitenangaben Beitrag:
9165--9171
Volltext / DOI:
doi:10.1021/jf051701o
Print-ISSN:
0021-8561
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