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Title:

Bioappearance and pharmacokinetics of bioactives upon coffee consumption

Document type:
Zeitschriftenaufsatz
Author(s):
Lang, Roman; Dieminger, Natalie; Beusch, Anja; Lee, Yu-Mi; Dunkel, Andreas; Suess, Barbara; Skurk, Thomas; Wahl, Anika; Hauner, Hans; Hofmann, Thomas
Abstract:
Habitual consumption of medium amounts of coffee over the whole life-span is hypothesized to reduce the risk to develop diabetes type 2 (DM2) and Alzheimer's disease (AD). To identify putative bioactive coffee-derived metabolites, first, pooled urine from coffee drinkers and non-coffee drinkers were screened by UPLC-HDMS. After statistical data analysis, trigonelline, dimethylxanthines and monomethylxanthines, and ferulic acid conjugates were identified as the major metabolites found after coffe...     »
Journal title:
Analytical and Bioanalytical Chemistry
Year:
2013
Journal volume:
405
Journal issue:
26
Pages contribution:
8487--8503
Fulltext / DOI:
doi:10.1007/s00216-013-7288-0
Print-ISSN:
1618-2642
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