Benutzer: Gast  Login
Titel:

Ces locus embedded proteins control the non-ribosomal synthesis of the cereulide toxin in emetic Bacillus cereus on multiple levels

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Lücking, Genia; Frenzel, Elrike; Rütschle, Andrea; Marxen, Sandra; Stark, Timo D.; Hofmann, Thomas; Scherer, Siegfried; Ehling-Schulz, Monika
Abstract:
The emetic toxin cereulide produced by Bacillus cereus is synthesized by the modular enzyme complex Ces that is encoded on a pXO1-like megaplasmid. To decipher the role of the genes adjacent to the structural genes cesA/cesB, coding for the non-ribosomal peptide synthetase (NRPS), gene inactivation- and overexpression mutants of the emetic strain F4810/72 were constructed and their impact on cereulide biosynthesis was assessed. The hydrolase CesH turned out to be a part of the complex regulatory...     »
Zeitschriftentitel:
Frontiers in microbiology
Jahr:
2015
Band / Volume:
6
Seitenangaben Beitrag:
1101
Volltext / DOI:
doi:10.3389/fmicb.2015.01101
Print-ISSN:
1664-302X
 BibTeX