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Titel:

Joint Base-Calling of Two DNA Sequences With Factor Graphs

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Xiaomeng Shi; Lun, D.S.; Medard, M.; Koetter, R.; Meldrim, J.C.; Barry, A.J.
Abstract:
Automated estimation of DNA base-sequences is an important step in genomics and in many other emerging fields in biological and medical sciences. Current automated sequencers process single strands only. To improve the utility of existing technologies, we propose to mix two independent strands prior to electrophoresis, and base-call jointly by applying the sum-product algorithm on factor graphs. We first present a statistical model for DNA sequencing data and examine the model parameters. A prac...     »
Zeitschriftentitel:
IEEE Transactions on Information Theory
Jahr:
2010
Band / Volume:
Vol. 56
Jahr / Monat:
2010-02
Quartal:
1. Quartal
Monat:
Feb
Heft / Issue:
2
Seitenangaben Beitrag:
724-733
Sprache:
en
WWW:
http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=5420276&tag=1
TUM Einrichtung:
Lehrstuhl für Nachrichtentechnik
Format:
Text
Letzte Änderung:
30.06.2010
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