First structure-activity relationship of 17&beta;-hydroxysteroid dehydrogenase type 14 nonsteroidal inhibitors and crystal structures in complex with the enzyme.

Titel:: First structure-activity relationship of 17β -hydroxysteroid dehydrogenase type 14 nonsteroidal inhibitors and crystal structures in complex with the enzyme.
Autor(en):: Braun, F. ; Bertoletti, N. ; Möller, G. ; Adamski, J. ; Steinmetzer, T. ; Salah, M. ; Abdelsamie, A.S. ; Van Koppen, C.J. ; Heine, A. ; Klebe, G. ; Marchais-Oberwinkler, S.
Stichworte:: Genetics and Epidemiology
Zeitschriftentitel:: J. Med. Chem.
Jahr:: 2016
Band / Volume:: 59
Seitenangaben Beitrag:: 10719-10737
Volltext / DOI:: doi:10.1021/acs.jmedchem.6b01436
E-ISSN:: 0022-2623
Impact Factor:: 5,589
Hinweise:: Research Programmes: Genes and Environment in Common Diseases
TUM Einrichtung:: Institute of Experimental Genetics (IEG)
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First structure-activity relationship of 17&beta; -hydroxysteroid dehydrogenase type 14 nonsteroidal inhibitors and crystal structures in complex with the enzyme.