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- Titel:
Role of enteric glia in intestinal physiology: effects of the gliotoxin fluorocitrate on motor and secretory function.
- Dokumenttyp:
- Zeitschriftenaufsatz
- Autor(en):
- Nasser, Yasmin; Fernandez, Ester; Keenan, Catherine M.; Ho, Winnie; Oland, Lorraine D.; Tibbles, Lee Anne; Schemann, Michael; MacNaughton, Wallace K.; Ruhl, Anne; Sharkey, Keith A.
- Abstract:
- The role of enteric glia in gastrointestinal physiology remains largely unexplored. We examined the actions of the gliotoxin fluorocitrate (FC) on intestinal motility, secretion, and inflammation after assessing its efficacy and specificity in vitro. FC (100 microM) caused a significant decrease in the phosphorylation of the glucose analog
- Stichworte:
- Image Processing, Computer-Assisted, Mice, Inbred C57BL, Cells, Cultured, Immunohistochemistry, Animals, Mice, Male, Muscle Contraction/drug effects, Rats, 4-Chloro-7-nitrobenzofurazan/analogs & derivatives/pharmacology, Citrates/*toxicity, Colitis/chemically induced, Deoxyglucose/analogs & derivatives/pharmacology, Enteric Nervous System/cytology/*drug effects, Gastrointestinal Diseases/*chemically induced/pathology, Gastrointestinal Motility/drug effects/*physiology, Gastrointestinal Transit/d... »
- Zeitschriftentitel:
- American journal of physiology. Gastrointestinal and liver physiology
- Jahr:
- 2006
- Band / Volume:
- 291
- Monat:
- nov
- Heft / Issue:
- 5
- Seitenangaben Beitrag:
- G912--927
- Sprache:
- eng
- Volltext / DOI:
- doi:10.1152/ajpgi.00067.2006
- Print-ISSN:
- 0193-1857 0193-1857
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