New insights into human 17&beta;-hydroxysteroid dehydrogenase type 14: First crystal structures in complex with a steroidal ligand and with a potent non-steroidal inhibitor.

Title:: New insights into human 17β -hydroxysteroid dehydrogenase type 14: First crystal structures in complex with a steroidal ligand and with a potent non-steroidal inhibitor.
Author(s):: Bertoletti, N. ; Braun, F. ; Lepage, M. ; Möller, G. ; Adamski, J. ; Heine, A. ; Klebe, G. ; Marchais-Oberwinkler, S.
Keywords:: Genetics and Epidemiology
Journal title:: J. Med. Chem.
Year:: 2016
Journal volume:: 59
Pages contribution:: 6961-6967
Fulltext / DOI:: doi:10.1021/acs.jmedchem.6b00293
E-ISSN:: 0022-2623
Impact Factor:: 5,589
Notes:: Research Programmes: Genes and Environment in Common Diseases
TUM Institution:: Institute of Experimental Genetics (IEG)
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New insights into human 17&beta; -hydroxysteroid dehydrogenase type 14: First crystal structures in complex with a steroidal ligand and with a potent non-steroidal inhibitor.