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- Title:
Building ProteomeTools based on a complete synthetic human proteome
- Document type:
- Zeitschriftenaufsatz
- Author(s):
- Zolg, Daniel P; Wilhelm, Mathias; Schnatbaum, Karsten; Zerweck, Johannes; Knaute, Tobias; Delanghe, Bernard; Bailey, Derek J; Gessulat, Siegfried; Ehrlich, Hans-Christian; Weininger, Maximilian; Yu, Peng; Schlegl, Judith; Kramer, Karl; Schmidt, Tobias; Kusebauch, Ulrike; Deutsch, Eric W; Aebersold, Ruedi; Moritz, Robert L; Wenschuh, Holger; Moehring, Thomas; Aiche, Stephan; Huhmer, Andreas; Reimer, Ulf; Kuster, Bernhard
- Abstract:
- We describe ProteomeTools, a project building molecular and digital tools from the human proteome to facilitate biomedical research. Here we report the generation and multimodal liquid chromatography–tandem mass spectrometry analysis of >330,000 synthetic tryptic peptides representing essentially all canonical human gene products, and we exemplify the utility of these data in several applications. The resource (available at http://www.proteometools.org) will be extended to >1 million peptides, a... »
- Journal title:
- Nature Methods
- Year:
- 2017
- Journal volume:
- 14
- Journal issue:
- 3
- Pages contribution:
- 259-262
- Fulltext / DOI:
- doi:10.1038/nmeth.4153
- Publisher:
- Springer Science and Business Media LLC
- E-ISSN:
- 1548-70911548-7105
- Date of publication:
- 30.01.2017
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