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Lo, Wan-Lin;Kuhlmann, Miriam;Rizzuto, Gabrielle;Ekiz, H. Atakan;Kolawole, Elizabeth M.;Revelo, Monica P.;Andargachew, Rakieb;Li, Zhongmei;Tsai, Yuan-Li;Marson, Alexander;Evavold, Brian D.;Zehn, Dietmar;Weiss, Arthur
A single-amino acid substitution in the adaptor LAT accelerates TCR proofreading kinetics and alters T-cell selection, maintenance and function
Nature Immunology
2023
24
4
676-689

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Marx, Anna-Friederike;Kallert, Sandra M.;Brunner, Tobias M.;Villegas, José A.;Geier, Florian;Fixemer, Jonas;Abreu-Mota, Tiago;Reuther, Peter;Bonilla, Weldy V.;Fadejeva, Jelizaveta;Kreutzfeldt, Mario;Wagner, Ingrid;Aparicio-Domingo, Patricia;Scarpellino, Leo;Charmoy, Mélanie;Utzschneider, Daniel T.;Hagedorn, Claudia;Lu, Min;Cornille, Karen;Stauffer, Karsten;Kreppel, Florian;Merkler, Doron;Zehn, Dietmar;Held, Werner;Luther, Sanjiv A.;Löhning, Max;Pinschewer, Daniel D.
The alarmin interleukin-33 promotes the expansion and preserves the stemness of Tcf-1+ CD8+ T cells in chronic viral infection
Immunity
2023
56
4
813-828.e10

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Scherer, Stefanie;Oberle, Susanne G.;Kanev, Kristiyan;Gerullis, Ann-Katrin;Wu, Ming;de Almeida, Gustavo P.;Puleston, Daniel J.;Baixauli, Francesc;Aly, Lilian;Greco, Alessandro;Nizharadze, Tamar;Becker, Nils B.;Hoesslin, Madlaina v.;Donhauser, Lara V.;Berner, Jacqueline;Chu, Talyn;McNamara, Hayley A.;Esencan, Zeynep;Roelli, Patrick;Wurmser, Christine;Kleiter, Ingo;Vehreschild, Maria J. G. T.;Mayer, Christoph A.;Knolle, Percy;Klingenspor, Martin;Fumagalli, Valeria;Iannacone, Matteo;Prlic, Martin;Korn, Thomas;Pearce, Erika L.;Höfer, Thomas;Schulz, Anna M.;Zehn, Dietmar
Pyrimidine de novo synthesis inhibition selectively blocks effector but not memory T cell development
Nature Immunology
2023
24
3
501-515

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Soerens, Andrew G.;Künzli, Marco;Quarnstrom, Clare F.;Scott, Milcah C.;Swanson, Lee;Locquiao, JJ.;Ghoneim, Hazem E.;Zehn, Dietmar;Youngblood, Benjamin;Vezys, Vaiva;Masopust, David
Functional T cells are capable of supernumerary cell division and longevity
Nature
2023
614
7949
762-766

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Tsui, Carlson;Kretschmer, Lorenz;Rapelius, Svenja;Gabriel, Sarah S.;Chisanga, David;Knöpper, Konrad;Utzschneider, Daniel T.;Nüssing, Simone;Liao, Yang;Mason, Teisha;Torres, Santiago Valle;Wilcox, Stephen A.;Kanev, Krystian;Jarosch, Sebastian;Leube, Justin;Nutt, Stephen L.;Zehn, Dietmar;Parish, Ian A.;Kastenmüller, Wolfgang;Shi, Wei;Buchholz, Veit R.;Kallies, Axel
MYB orchestrates T cell exhaustion and response to checkpoint inhibition
Nature
2022
609
7926
354-360

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Zehn, Dietmar;Thimme, Robert;Lugli, Enrico;de Almeida, Gustavo Pereira;Oxenius, Annette
‘Stem-like’ precursors are the fount to sustain persistent CD8+ T cell responses
Nature Immunology
2022
23
6
836-847

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von Hoesslin, Madlaina;Kuhlmann, Miriam;de Almeida, Gustavo Pereira;Kanev, Kristiyan;Wurmser, Christine;Gerullis, Ann-Katrin;Roelli, Patrick;Berner, Jacqueline;Zehn, Dietmar
Secondary infections rejuvenate the intestinal CD103 + tissue-resident memory T cell pool
Science Immunology
2022
7
77

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Schulz, Anna M.;Zebley, Caitlin C.;Youngblood, Ben;Zehn, Dietmar
Tapping the keg of discovery to advance T cell therapy
Nature Immunology
2023
24
2
213-215

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Schulz, Anna M;Zehn, Dietmar
Mastering an exhausting marathon: how CD8 + T cells fine‐tune metabolic fitness
Immunology & Cell Biology
2022
100
2
83-86

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Koerber, Nina;Priller, Alina;Yazici, Sarah;Bauer, Tanja;Cheng, Cho-Chin;Mijočević, Hrvoje;Wintersteller, Hannah;Jeske, Samuel;Vogel, Emanuel;Feuerherd, Martin;Tinnefeld, Kathrin;Winter, Christof;Ruland, Jürgen;Gerhard, Markus;Haller, Bernhard;Christa, Catharina;Zelger, Otto;Roggendorf, Hedwig;Halle, Martin;Erber, Johanna;Lingor, Paul;Keppler, Oliver;Zehn, Dietmar;Protzer, Ulrike;Knolle, Percy A.
Dynamics of spike-and nucleocapsid specific immunity during long-term follow-up and vaccination of SARS-CoV-2 convalescents
Nature Communications
2022
13
1