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Lier, Svenja;Sellmer, Andreas;Orben, Felix;Heinzlmeir, Stephanie;Krauß, Lukas;Schneeweis, Christian;Hassan, Zonera;Schneider, Carolin;Patricia Gloria Schäfer, Arlett;Pongratz, Herwig;Engleitner, Thomas;Öllinger, Rupert;Kuisl, Anna;Bassermann, Florian;Schlag, Christoph;Kong, Bo;Dove, Stefan;Kuster, Bernhard;Rad, Roland;Reichert, Maximilian;Wirth, Matthias;Saur, Dieter;Mahboobi, Siavosh;Schneider, Günter
A novel Cereblon E3 ligase modulator with antitumor activity in gastrointestinal cancer
Bioorganic Chemistry
2022
119
105505

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Mergner, Julia;Kuster, Bernhard
Plant Proteome Dynamics
Annual Review of Plant Biology
2022
73
1
67-92

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Falcomatà, Chiara;Bärthel, Stefanie;Widholz, Sebastian A.;Schneeweis, Christian;Montero, Juan José;Toska, Albulena;Mir, Jonas;Kaltenbacher, Thorsten;Heetmeyer, Jeannine;Swietlik, Jonathan J.;Cheng, Jing-Yuan;Teodorescu, Bianca;Reichert, Oliver;Schmitt, Constantin;Grabichler, Kathrin;Coluccio, Andrea;Boniolo, Fabio;Veltkamp, Christian;Zukowska, Magdalena;Vargas, Angelica Arenas;Paik, Woo Hyun;Jesinghaus, Moritz;Steiger, Katja;Maresch, Roman;Öllinger, Rupert;Ammon, Tim;Baranov, Olga;Robles, Maria S.;Rechenberger, Julia;Kuster, Bernhard;Meissner, Felix;Reichert, Maximilian;Flossdorf, Michael;Rad, Roland;Schmidt-Supprian, Marc;Schneider, Günter;Saur, Dieter
Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment
Nature Cancer
2022
3
3
318-336

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Weiß, Lukas;Gaelings, Lana;Reiner, Tina;Mergner, Julia;Kuster, Bernhard;Fehér, Attila;Hensel, Götz;Gahrtz, Manfred;Kumlehn, Jochen;Engelhardt, Stefan;Hückelhoven, Ralph
Posttranslational modification of the RHO of plants protein RACB by phosphorylation and cross-kingdom conserved ubiquitination
PLOS ONE
2022
17
3
e0258924

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Steimbach, Raphael R.;Herbst-Gervasoni, Corey J.;Lechner, Severin;Stewart, Tracy Murray;Klinke, Glynis;Ridinger, Johannes;Géraldy, Magalie N. E.;Tihanyi, Gergely;Foley, Jackson R.;Uhrig, Ulrike;Kuster, Bernhard;Poschet, Gernot;Casero, Robert A., Jr.;Médard, Guillaume;Oehme, Ina;Christianson, David W.;Gunkel, Nikolas;Miller, Aubry K.
Aza-SAHA Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout
Journal of the American Chemical Society
2022
144
41
18861-18875

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Gabriel, Wassim;The, Matthew;Zolg, Daniel P.;Bayer, Florian P.;Shouman, Omar;Lautenbacher, Ludwig;Schnatbaum, Karsten;Zerweck, Johannes;Knaute, Tobias;Delanghe, Bernard;Huhmer, Andreas;Wenschuh, Holger;Reimer, Ulf;Médard, Guillaume;Kuster, Bernhard;Wilhelm, Mathias
Prosit-TMT: Deep Learning Boosts Identification of TMT-Labeled Peptides
Analytical Chemistry
2022
94
20
7181-7190

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Orben, Felix;Lankes, Katharina;Schneeweis, Christian;Hassan, Zonera;Jakubowsky, Hannah;Krauß, Lukas;Boniolo, Fabio;Schneider, Carolin;Schäfer, Arlett;Murr, Janine;Schlag, Christoph;Kong, Bo;Öllinger, Rupert;Wang, Chengdong;Beyer, Georg;Mahajan, Ujjwal M.;Xue, Yonggan;Mayerle, Julia;Schmid, Roland M.;Kuster, Bernhard;Rad, Roland;Braun, Christian J.;Wirth, Matthias;Reichert, Maximilian;Saur, Dieter;Schneider, Günter
Epigenetic drug screening defines a PRMT5 inhibitor–sensitive pancreatic cancer subtype
JCI Insight
2022
7
10

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Bozilovic, Jelena;Eing, Lorenz;Berger, Benedict-Tilman;Adhikari, Bikash;Weckesser, Janik;Berner, Nicola B.;Wilhelm, Stephanie;Kuster, Bernhard;Wolf, Elmar;Knapp, Stefan
Novel, highly potent PROTACs targeting AURORA-A kinase
Current Research in Chemical Biology
2022
2
100032

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Oeckl, Josef;Janovska, Petra;Adamcova, Katerina;Bardova, Kristina;Brunner, Sarah;Dieckmann, Sebastian;Ecker, Josef;Fromme, Tobias;Funda, Jiri;Gantert, Thomas;Giansanti, Piero;Hidrobo, Maria Soledad;Kuda, Ondrej;Kuster, Bernhard;Li, Yongguo;Pohl, Radek;Schmitt, Sabine;Schweizer, Sabine;Zischka, Hans;Zouhar, Petr;Kopecky, Jan;Klingenspor, Martin
Loss of UCP1 function augments recruitment of futile lipid cycling for thermogenesis in murine brown fat
Molecular Metabolism
2022
61
101499

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Lo, Wen-Ting;Belabed, Hassane;Kücükdisli, Murat;Metag, Juliane;Roske, Yvette;Prokofeva, Polina;Ohashi, Yohei;Horatscheck, André;Cirillo, Davide;Krauss, Michael;Schmied, Christopher;Neuenschwander, Martin;von Kries, Jens Peter;Médard, Guillaume;Kuster, Bernhard;Perisic, Olga;Williams, Roger L.;Daumke, Oliver;Payrastre, Bernard;Severin, Sonia;Nazaré, Marc;Haucke, Volker
Development of selective inhibitors of phosphatidylinositol 3-kinase C2α
Nature Chemical Biology
2022