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Title:

Analysis of the Sex-specific Variability of Blood Parameters in C3H Inbred Mice by Using Data from a Long-term, High-throughput Project.

Document type:
Zeitschriftenaufsatz
Author(s):
Aigner B, Rathkolb B, Hrabě de Angelis M, Wolf E
Abstract:
Mice are important models for biomedical research by providing the possibility of standardizing genetic background and environmental conditions, which both affect phenotypic variability. Use of both sexes in experiments is strongly recommended because of possible differences in the outcome. However, sex-specific phenotypic variability is discussed with regard to putative consequences on the group size which is necessary for achieving valid and reproducible results. Here, we retrospectively analy...     »
Keywords:
animal model, clinical chemistry, hematology, sex, variability
Journal title:
Physiological Research
Year:
2021
Journal volume:
Epub
Quarter:
1. Quartal
Month:
Mar
Reviewed:
ja
Language:
en
Fulltext / DOI:
doi:10.33549/physiolres.934577
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/33676383
WWW:
PDF
Publisher:
Published for the Institute of Physiology of the Czechoslovak Academy of Sciences by Academia, Pub. House of the Academy
Publisher address:
Prag
Print-ISSN:
0862-8408
E-ISSN:
1802-9973
Impact Factor:
1,655
Status:
Postprint / reviewed
TUM Institution:
Institute of Experimental Genetics (IEG)
Format:
Text
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