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Titel:

Functional characterization of two 20β-hydroxysteroid dehydrogenase type 2 homeologs from Xenopus laevis reveals multispecificity.

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Tokarz J, Schmitt SM, Möller G, Brändli AW, Adamski J
Abstract:
The African clawed frog, Xenopus laevis, is a versatile model for biomedical research and is largely similar to mammals in terms of organ development, anatomy, physiology, and hormonal signaling mechanisms. Steroid hormones control a variety of processes and their levels are regulated by hydroxysteroid dehydrogenases (HSDs). The subfamily of 20β-HSD type 2 enzymes currently comprises eight members from teleost fish and mammals. Here, we report the identification of three 20β-HSD type 2 genes in...     »
Stichworte:
20β-reduction; cortisone; frog; hsd20b2; hydroxysteroid dehydrogenase; steroid catabolism.
Zeitschriftentitel:
J Steroid Biochem Mol Biol
Jahr:
2021
Band / Volume:
Epub
Jahr / Monat:
2021-03
Quartal:
1. Quartal
Monat:
Mar
Seitenangaben Beitrag:
"-"
Reviewed:
ja
Sprache:
en
Volltext / DOI:
doi:10.1016/j.jsbmb.2021.105874
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/33722706
Verlag / Institution:
Pergamon, c1990-
Verlagsort:
Oxford ; New York, USA
Print-ISSN:
0960-0760
E-ISSN:
1879-1220
Impact Factor:
3,813
Status:
Postprint / reviewed
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