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Titel:

Using human intestinal biopsies to study the pathogenesis of irritable bowel syndrome.

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Nasser, Y.; Boeckxstaens, G. E.; Wouters, M. M.; Schemann, M.; Vanner, S.
Abstract:
BACKGROUND: Although animal models of the irritable bowel syndrome (IBS) have provided important insights, there are no models that fully express the features of this complex condition. One alternative approach is the use of human intestinal biopsies obtained during endoscopic procedures to examine peripheral mechanisms in this disorder. These studies have served to confirm the existence of peripheral pathways in humans with IBS and have provided many new mechanistic insights. Two general appr...     »
Stichworte:
Humans, Female, Male, Biopsy, visceral hyperalgesia, histamine, IBS, Intestines/*pathology/*physiopathology, Irritable Bowel Syndrome/etiology/*pathology/*physiopathology, mast cells, proteases
Zeitschriftentitel:
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society
Jahr:
2014
Band / Volume:
26
Monat:
apr
Heft / Issue:
4
Seitenangaben Beitrag:
455--469
Sprache:
eng
Volltext / DOI:
doi:10.1111/nmo.12316
Print-ISSN:
1365-2982 1350-1925
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