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Titel:

A lectin S-domain receptor kinase mediates lipopolysaccharide sensing in Arabidopsis thaliana

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Ranf, Stefanie; Gisch, Nicolas; Schäffer, Milena; Illig, Tina; Westphal, Lore; Knirel, Yuriy A.; Sánchez-Carballo, Patricia M.; Zähringer, Ulrich; Hückelhoven, Ralph; Lee, Justin; Scheel, Dierk
Abstract:
The sensing of microbe-associated molecular patterns (MAMPs) triggers innate immunity in animals and plants. Lipopolysaccharide (LPS) from Gram-negative bacteria is a potent MAMP for mammals, with the lipid A moiety activating proinflammatory responses via Toll-like receptor 4 (TLR4). Here we found that the plant Arabidopsis thaliana specifically sensed LPS of Pseudomonas and Xanthomonas. We isolated LPS-insensitive mutants defective in the bulb-type lectin S-domain-1 receptor-like kinase LORE (...     »
Stichworte:
Arabidopsis Proteins/genetics/immunology; Arabidopsis/drug effects/genetics/immunology/microbiology; Gene Expression Regulation, Plant/immunology; Lipopolysaccharides/pharmacology; Plant Immunity/genetics; Protein-Serine-Threonine Kinases/genetics/immunology; Pseudomonas syringae/chemistry/immunology; Signal Transduction; Tobacco/drug effects/genetics/immunology/microbiology; Transgenes; Xanthomonas campestris/chemistry/immunology
Zeitschriftentitel:
Nature immunology
Jahr:
2015
Band / Volume:
16
Heft / Issue:
4
Seitenangaben Beitrag:
426--433
Reviewed:
ja
Volltext / DOI:
doi:10.1038/ni.3124
Print-ISSN:
1529-2916
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