Molecular consequences of genetic and epigenetic factors can be explored by expression quantitative trait locus (eQTL) analysis and analogous association approaches. Applying these, we analyzed associations of DNA methylation with genetics and gene expression to improve our understanding of epigenetics. Additionally, we established a statistical power analysis framework to design cell type specific single cell eQTL studies and developed a new strategy for the detection of co-expression QTLs with single cell data.
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Molecular consequences of genetic and epigenetic factors can be explored by expression quantitative trait locus (eQTL) analysis and analogous association approaches. Applying these, we analyzed associations of DNA methylation with genetics and gene expression to improve our understanding of epigenetics. Additionally, we established a statistical power analysis framework to design cell type specific single cell eQTL studies and developed a new strategy for the detection of co-expression QTLs with...
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