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Title:

Determination of Compressibility and Relaxation Behavior of Yeast Cell Sediments by Analytical Centrifugation and Comparison with Deposit Formation on Membrane Surfaces

Document type:
Zeitschriftenaufsatz
Author(s):
Weinberger, Maria E.; Kulozik, Ulrich;
Abstract:
Separation of cells from produced biomolecules is a challenging task in many biotechnological downstream operations due to deposit formation of the retained cells, affecting permeation of the target product. Compression and relaxation behavior of cell deposits formed during filtration are important factors affecting operational performance. The determination of these factors by flux or pressure stepping experiments is time- and labor-intensive. In this work, we propose a screening method by anal...     »
Keywords:
bio-suspensions; BSA; Deposit layer formation; downstream processing; microfiltration; saccharomyces
Dewey Decimal Classification:
050 Zeitschriften, fortlaufende Sammelwerke
Journal title:
Membranes
Year:
2022
Journal volume:
12
Year / month:
2022-06
Quarter:
2. Quartal
Month:
Jun
Journal issue:
12
Pages contribution:
603
Covered by:
Web of Science
Reviewed:
ja
Language:
en
Fulltext / DOI:
doi:10.3390/membranes12060603
Print-ISSN:
2077-0375
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