Researchers at the TUM Institute for Advanced Study successfully improved the functionality of solid-state nanopores by fitting them with nanoplate covers made of DNA. Inspired by the Japanese paper-folding art of origami, the DNA strands are programmed to fold into custom designed structures with specific chemical properties. This opens the door to measuring individual molecules and thus label-free screening of proteins. The picture shows a DNA origami nanoplate functioning as a “gatekeeper” for a solid-state nanopore sensor.     «

Researchers at the TUM Institute for Advanced Study successfully improved the functionality of solid-state nanopores by fitting them with nanoplate covers made of DNA. Inspired by the Japanese paper-folding art of origami, the DNA strands are programmed to fold into custom designed structures with specific chemical properties. This opens the door to measuring individual molecules and thus label-free screening of proteins. The picture shows a DNA origami nanoplate functioning as a “gatekeeper” fo...     »