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Titel:

Therapy-refractory gastrointestinal motility disorder in a child with c-kit mutations.

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Breuer, Christian; Oh, Jun; Molderings, Gerhard-J.; Schemann, Michael; Kuch, Birgit; Mayatepek, Ertan; Adam, Rudiger
Abstract:
Constipation and fecal impaction are frequent and distressing complaints in pediatric gastroenterology. Especially in neurologically handicapped children, treatment of severe forms of slow-transit constipation (STC) can be difficult. In the majority of cases, STC is of unknown etiology. However, in recent years, there is growing evidence that interstitial cells of Cajal (ICCs), which serve as electrical pacemakers and generate spontaneous electrical slow waves in the gastrointestinal tract, migh...     »
Stichworte:
Humans, Adolescent, Male, *Gastrointestinal Transit, *Mutation, Constipation/*etiology, Interstitial Cells of Cajal/*pathology, Proto-Oncogene Proteins c-kit/*genetics
Zeitschriftentitel:
World journal of gastroenterology
Jahr:
2010
Band / Volume:
16
Monat:
sep
Heft / Issue:
34
Seitenangaben Beitrag:
4363--4366
Sprache:
eng
Print-ISSN:
2219-2840 1007-9327
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