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Title:

Toward a disruptive, minimally invasive small finger joint implant concept: Cellular and molecular interactions with materials in vivo

Document type:
Zeitschriftenaufsatz
Author(s):
Ben Amara, Heithem; Farjam, Pardis; Lutz, Theresa M.; Omar, Omar; Palmquist, Anders; Lieleg, Oliver; Browne, Martin; Taylor, Andy; Verkerke, Gijsbertus J.; Rouwkema, Jeroen; Thomsen, Peter
Abstract:
Osteoarthritis (OA) poses significant therapeutic challenges, particularly OA that affects the hand. Currently available treatment strategies are often limited in terms of their efficacy in managing pain, regulating invasiveness, and restoring joint function. The APRICOTⓇ implant system developed by Aurora Medical Ltd (Chichester, UK) introduces a minimally invasive, bone-conserving approach for treating hand OA (https://apricot-project.eu/). By utilizing polycarbonate urethane (PCU), this impla...     »
Keywords:
Animal models; Biocompatibility; Gene expression; Osteoarthritis; Polyurethanes
Dewey Decimal Classification:
500 Naturwissenschaften
Journal title:
Acta Biomaterialia
Year:
2024
Journal volume:
183
Pages contribution:
130-145
Covered by:
Scopus
Reviewed:
ja
Language:
en
Fulltext / DOI:
doi:10.1016/j.actbio.2024.05.042
WWW:
https://www.sciencedirect.com/science/article/pii/S1742706124002897
Publisher:
Elsevier BV
E-ISSN:
1742-7061
Status:
Verlagsversion / published
Date of publication:
01.07.2024
Semester:
SS 24
TUM Institution:
Fachgebiet für Biomechanik, MW
Format:
Bild/Text
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