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Title:

Separation of glycossylated caseinomacropeptide at pilot scale using membrane adsorption in direct-capture mode

Document type:
Zeitschriftenaufsatz
Author(s):
Kreuß, M.; Kulozik, U.
Abstract:
A direct-capture anion-exchange membrane adsorption process for the separation of a pure glycosylated (gCMP) fraction of caseinomacropeptide (CMP)was successfully developed at pilot plant scale. The method was evolved using a commercial CMP isolate as feedstock as well as fresh sweet whey from skim milk. The former resulted in a binding capacity (BC) of 0.28mggCMP/cm2 membrane surface with a purity of 97% while the latter afforded agCMPfraction with a purity of 91% and a BC of 0.21mggCMP/cm2 mem...     »
Keywords:
Caseinomacropeptid; Glykomacropeptid; Membrane adsorber; membrane adsprotion chromatography; Repeated elution; Scale-up; Whey protein fractionation
Journal title:
Journal of Chromatography A
Year:
2009
Journal volume:
12
Journal issue:
50
Pages contribution:
8771--8777
Fulltext / DOI:
doi:10.1016/j.chroma.2009.01.084
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