The combination of Positron Emission Tomography (PET) and Computed Tomography (CT) has resulted in improved diagnostic accuracy and enhanced clinical workflows, demonstrating the potential of multimodality imaging and raising the interest for the combination of PET with Magnetic Resonance Imaging (MRI). This thesis deals with the problems of patient motion and photon attenuation, relevant to PET imaging and its combination with CT and MRI. Three applications are addressed: the correction of breathing and cardiac beating by means of gated acquisitions; the PET-CT misregistration in cardiac imaging and the resulting diagnostic problems due to CT-based photon attenuation correction; and the generation of MRI-based attenuation maps through suitable MRI sequences and automatic tissue segmentation.
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The combination of Positron Emission Tomography (PET) and Computed Tomography (CT) has resulted in improved diagnostic accuracy and enhanced clinical workflows, demonstrating the potential of multimodality imaging and raising the interest for the combination of PET with Magnetic Resonance Imaging (MRI). This thesis deals with the problems of patient motion and photon attenuation, relevant to PET imaging and its combination with CT and MRI. Three applications are addressed: the correction of brea...
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