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Document type:
In Vitro; Journal Article; Research Support, Non-U.S. Gov't 
Author(s):
Groh, A; de Kock, CP; Wimmer, VC; Sakmann, B; Kuner, T 
Title:
Driver or coincidence detector: modal switch of a corticothalamic giant synapse controlled by spontaneous activity and short-term depression. 
Abstract:
Giant synapses between layer 5B (L5B) neurons of somatosensory (barrel) cortex and neurons of the posteromedial nucleus (POm) of thalamus reside in a key position of the cortico-thalamo-cortical (CTC) loop, yet their synaptic properties and contribution to CTC information processing remain poorly understood. Fluorescence-guided local stimulation of terminals were combined with postsynaptic whole-cell recordings in thalamus to study synaptic transmission at an identified giant synapse. We found l...    »
 
Journal title abbreviation:
J Neurosci 
Year:
2008 
Journal volume:
28 
Journal issue:
39 
Pages contribution:
9652-63 
Language:
eng 
Print-ISSN:
0270-6474 
TUM Institution:
Institut für Neurowissenschaften