Merold, Veronika;Bekere, Indra;Kretschmer, Stefanie;Schnell, Adrian F;Kmiec, Dorota;Sivarajan, Rinu;Lammens, Katja;Liu, Rou;Mergner, Julia;Teppert, Julia;Hirschenberger, Maximilian;Henrici, Alexander;Hammes, Sarah;Buder, Kathrin;Weitz, Marcus;Hackmann, Karl;Koenig, Lars M;Pichlmair, Andreas;Schwierz, Nadine;Sparrer, Konstantin M J;Lee-Kirsch, Min Ae;de Oliveira Mann, Carina C
Structural basis for OAS2 regulation and its antiviral function.
Mol Cell
2025
85
11
2176-2193.e13

Appelman, Monique D;Nguyen, Thuc-Anh;Oswald, Andreas;Lucko, Aaron;Paulusma, Coen C;Protzer, Ulrike;van de Graaf, Stan F J
NTCP ubiquitination enables HBV infection.
JHEP Rep
2025
7
11

Rust, Lauren N;Wettengel, Jochen M;Biswas, Sreya;Ryu, Junghyun;Piekarski, Nadine;Yusova, Sofiya;Lutz, Savannah S;Naldiga, Spandana;Hinrichs, Brayden J;Sullivan, Michelle N;Lo, Jamie O;Protzer, Ulrike;Smedley, Jeremy V;Sacha, Jonah B;Hanna, Carol B;Bimber, Benjamin N;Hennebold, Jon D;Burwitz, Benjamin J
Liver-specific transgenic expression of human NTCP in rhesus macaques confers HBV susceptibility on primary hepatocytes.
Proc Natl Acad Sci U S A
2025
122
7

M Bader, Stefanie;Calleja, Dale J;Devine, Shane M;Kuchel, Nathan W;Lu, Bernadine G C;Wu, Xinyu;Birkinshaw, Richard W;Bhandari, Reet;Loi, Katie;Volpe, Rohan;Khakham, Yelena;Au, Amanda E;Blackmore, Timothy R;Mackiewicz, Liana;Dayton, Merle;Schaefer, Jan;Scherer, Lena;Stock, Angus T;Cooney, James P;Schoffer, Kael;Maluenda, Ana;Kleeman, Elizabeth A;Davidson, Kathryn C;Allison, Cody C;Ebert, Gregor;Chen, Gong;Katneni, Kasiram;Klemm, Theresa A;Nachbur, Ueli;Georgy, Smitha Rose;Czabotar, Peter E;Hannan, Anthony J;Putoczki, Tracy L;Tanzer, Maria;Pellegrini, Marc;Lechtenberg, Bernhard C;Charman, Susan A;Call, Melissa J;Mitchell, Jeffrey P;Lowes, Kym N;Lessene, Guillaume;Doerflinger, Marcel;Komander, David
A novel PLpro inhibitor improves outcomes in a pre-clinical model of long COVID.
Nat Commun
2025
16
1

Du, Shunda;Wisskirchen, Karin;Zhang, Ke;Protzer, Ulrike
Correspondence to editorial on "Genetically-modified, redirected T cells target hepatitis B surface antigen-positive hepatocytes and hepatocellular carcinoma lesions in a clinical setting".
Clin Mol Hepatol
2025
31
1
e44-e47

Wu, Xiang'an;Quan, Dongmei;Li, Wei;Wisskirchen, Karin;Wu, Wei;Zhou, Yuhong;Liu, Yun-Peng;Wan, Xueshuai;Wang, Xiaorui;Zhang, Xuxu;Yang, Lu;Zheng, Mengyao;Zhang, Ke;Protzer, Ulrike;Du, Shunda;Qu, Xiujuan
Clinical results of an HBV-specific T-cell receptor-T-cell therapy (SCG101) in patients with HBV-related hepatocellular carcinoma treated in an investigator-initiated, interventional trial.
Gut
2025
75
1
147-160

Klute, Susanne;Nchioua, Rayhane;Cordsmeier, Arne;Vishwakarma, Jyoti;Koepke, Lennart;Alshammary, Hala;Jung, Christoph;Hirschenberger, Maximilian;Hoenigsperger, Helene;Fischer, Jana-Romana;Sivarajan, Rinu;Zech, Fabian;Stenger, Steffen;Serra-Moreno, Ruth;Gonzalez-Reiche, Ana Silvia;Sordillo, Emilia Mia;van Bakel, Harm;Simon, Viviana;Kirchhoff, Frank;Jacob, Timo;Kmiec, Dorota;Pichlmair, Andreas;Ensser, Armin;Sparrer, Konstantin Maria Johannes
Mutation T9I in Envelope confers autophagy resistance to SARS-CoV-2 Omicron.
iScience
2025
28
7

O'Connor, Tracy;Zhou, Xiaolan;Kosla, Jan;Adili, Arlind;Beccaria, Maria Garcia;Kotsiliti, Elena;Pfister, Dominik;Johlke, Anna-Lena;Sinha, Ankit;Sankowski, Roman;Schick, Markus;Lewis, Richard;Dokalis, Nikolaos;Seubert, Bastian;Höchst, Bastian;Inverso, Donato;Heide, Danijela;Zhang, Wenlong;Weihrich, Petra;Manske, Katrin;Wohlleber, Dirk;Anton, Martina;Hoellein, Alexander;Seleznik, Gitta;Bremer, Juliane;Bleul, Sabine;Augustin, Hellmut G;Scherer, Florian;Koedel, Uwe;Weber, Achim;Protzer, Ulrike;Förster, Reinhold;Wirth, Thomas;Aguzzi, Adriano;Meissner, Felix;Prinz, Marco;Baumann, Bernd;Höpken, Uta E;Knolle, Percy A;von Baumgarten, Louisa;Keller, Ulrich;Heikenwalder, Mathias
Age-Related Gliosis Promotes Central Nervous System Lymphoma through CCL19-Mediated Tumor Cell Retention.
Cancer Cell
2025
43
7
1377-1384

Luo, Jie;Molbay, Muge;Chen, Ying;Horvath, Izabela;Kadletz, Karoline;Kick, Benjamin;Zhao, Shan;Al-Maskari, Rami;Singh, Inderjeet;Ali, Mayar;Bhatia, Harsharan Singh;Minde, David-Paul;Negwer, Moritz;Hoeher, Luciano;Calandra, Gian Marco;Groschup, Bernhard;Su, Jinpeng;Kimna, Ceren;Rong, Zhouyi;Galensowske, Nikolas;Todorov, Mihail Ivilinov;Jeridi, Denise;Ohn, Tzu-Lun;Roth, Stefan;Simats, Alba;Singh, Vikramjeet;Khalin, Igor;Pan, Chenchen;Arús, Bernardo A;Bruns, Oliver T;Zeidler, Reinhard;Liesz, Arthur;Protzer, Ulrike;Plesnila, Nikolaus;Ussar, Siegfried;Hellal, Farida;Paetzold, Johannes;Elsner, Markus;Dietz, Hendrik;Erturk, Ali
Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning.
Nat Biotechnol
2025
43
12
2009-2022

Keller, Franziska;Chua, Robert Lorenz;Trefzer, Timo;Jechow, Katharina;Bauersfeld, Liane;Beier, Fabian;Sagar;Sogukpinar, Özlem;Rusignuolo, Giuseppe;Rizzi, Marta;Eils, Roland;Pichlmair, Andreas;Binder, Marco;Bengsch, Bertram;Neumann-Haefelin, Christoph;Lohmann, Volker;Boettler, Tobias;Conrad, Christian;Thimme, Robert;Hofmann, Maike
Differentiation-associated ISG expression of NK cells in chronic viral infection.
iScience
2025
28
9