Caceres, Amanda;Shibata, Noreene M;Davalos-Gutierrez, Christian D;Sarode, Gaurav V;Hussan, Hisham;Bettencourt, Margarida;Fontes, Adriana;Zischka, Hans;Lutsenko, Svetlana;Heffern, Marie C;Medici, Valentina
Inactivation of Atp7b copper transporter in intestinal epithelial cells is associated with altered lipid processing and cell growth machinery independent from hepatic copper accumulation and severity of liver histology.
Am J Pathol
2025

Lynderup, Emilie Munk;Vendelbo, Mikkel Holm;Kirk, Frederik Teicher;Vase, Karina Højrup;Alstrup, Aage Kristian Olsen;Rieder, Tamara;DiSpirito, Alan A;Semrau, Jeremy D;Laursen, Tea Lund;Ott, Peter;Zischka, Hans;Sandahl, Thomas Damgaard
Methanobactin rapidly facilitates biliary copper excretion in a Wilson disease rat model visualised by 64Cu PET/MRI.
Br J Pharmacol
2025

Bremer, Juliane;Nagel, Judith;Zschüntzsch, Jana;Zajt, Kamil K;Palaz, Tayfun;Blank, Thomas;Ikis, Aylin;Fischer, Laura A;Sensmeyer, Anna S M;Wiechers, Lara;Reichelt, Josef J;Hofmann, Kai P;Wolf, Monika J;Leuchtenberger, Corinna;Tripathi, Priyanka;Einer, Claudia;Zischka, Hans;Rothermel, Ulrike;Eck, Anna-L;Reimann, Regina;Kana, Veronika;Rushing, Elisabeth;Aguzzi, Adriano;Prinz, Marco;Liebetanz, David;Odoardi, Francesca;Kuo, Chao-Chung;Weis, Joachim;Kraft, Florian;Schmidt, Jens;Heikenwälder, Mathias
Mutual reinforcement of lymphotoxin-driven myositis and impaired autophagy in murine muscle.
Brain
2025
148
12
4461-4481

Deschler, Sebastian;Pohl-Topcu, Junika;Ramsauer, Lukas;Meiser, Philippa;Erlacher, Sophia;Schenk, Robin P;Maurer, H Carlo;Shen, Peng;Kager, Juliane;Zink, Joseph;Pistrenko, Karyna;Monte, Enric Redondo;Weber, Julius;Wasmaier, Lena;Laschinger, Melanie;Hüser, Norbert;Geisler, Fabian;Thorburn, Douglas;Nieß, Hanno;Wiedemann, Gabriela M;Zischka, Hans;Heikenwälder, Mathias;Kleigrewe, Karin;Mogler, Carolin;Böttcher, Jan P;Knolle, Percy A;Schmid, Roland M;Böttcher, Katrin
Polyunsaturated fatty acid-induced metabolic exhaustion and ferroptosis impair the anti-tumour function of MAIT cells in MASLD.
J Hepatol
2025
83
6
1364-1378

Jauch, A T;Sailer, J;Braun, J;Czeslik, E;Geyer, J;Eberhagen, C;Vollmar, A M;Zischka, H;Sieber, S A;Zahler, S
Neocarzilin A induces apoptosis and mitochondrial disturbance by targeting reticulon 4-mediated endoplasmic reticulum stress.
Cell Death Discov
2025
11
1

Sailer, Judith;Schmitt, Sabine;Zischka, Hans;Gnaiger, Erich
Direct Effects of Clinically Relevant Antibiotics on Mitochondrial Respiration.
Int J Mol Sci
2025
26
11

Petruzzelli, Raffaella;Catalano, Federico;Crispino, Roberta;Polishchuk, Elena V;Elia, Mariantonietta;Masone, Antonio;Lavigna, Giada;Grasso, Anna;Battipaglia, Maria;Sepe, Lucia Vittoria;Akdogan, Banu;Reinold, Quirin;Del Prete, Eugenio;Carrella, Diego;Torella, Annalaura;Nigro, Vincenzo;Caruso, Enrico;Innocenti, Nicole;Biasini, Emiliano;Puchkova, Ludmila V;Indrieri, Alessia;Ilyechova, Ekaterina Y;Piccolo, Pasquale;Zischka, Hans;Chiesa, Roberto;Polishchuk, Roman S
Prion protein promotes copper toxicity in Wilson disease.
Nat Commun
2025
16
1

Michaelis, Vivien;Klemens, Laura;Thiel, Alicia;Gremme, Anna;Schwarz, Maria;Kipp, Anna P;Zischka, Hans
Revealing mercury species-specific transfer and toxicity mechanisms in placental trophoblasts.
Chemosphere
2025
370

Białobrodzka, Emilia;Flis, Damian Jozef;Akdogan, Banu;Borkowska, Andzelika;Wieckowski, Mariusz Roman;Antosiewicz, Jedrzej;Zischka, Hans;Dzik, Katarzyna Patrycja;Kaczor, Jan Jacek;Ziolkowski, Wieslaw
Amyotrophic Lateral Sclerosis and swim training affect copper metabolism in skeletal muscle in a mouse model of disease.
Muscle Nerve
2024
70
5
1111-1118

Fontes, Adriana;Jauch, Adrian T;Sailer, Judith;Engler, Jonas;Azul, Anabela Marisa;Zischka, Hans
Metabolic Derangement of Essential Transition Metals and Potential Antioxidant Therapies.
Int J Mol Sci
2024
25
14