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- Title:
Efficacy of an app-based multimodal lifestyle intervention on body weight in persons with obesity: results from a randomized controlled trial.
- Document type:
- Randomized Controlled Trial; Journal Article
- Author(s):
- Gemesi, Kathrin; Winkler, Stefanie; Schmidt-Tesch, Susanne; Schederecker, Florian; Hauner, Hans; Holzapfel, Christina
- Abstract:
- BACKGROUND: Despite an increasing number of smartphone applications (apps) addressing weight management, data on the effect of app-based multimodal obesity treatment approaches on weight loss is limited. This study aimed to examine the effect of a digital multimodal weight loss intervention program delivered by an app on body weight in persons with obesity. METHODS: For this single-centre randomized controlled study, 168 adults with a body mass index (BMI) between 30.0 and 40.0 kg/m2 without severe comorbidities were recruited in the region of Munich and randomized into two intervention groups. The ADHOC group received an app-based multimodal weight loss program from baseline on for 12 weeks plus 12 weeks of follow-up. The EXPECT group received the app-based intervention for 12 weeks after 12 weeks of "waiting" (no intervention). Anthropometric data, data on quality of life (EuroQol, EQ-5D-5L), and app usage data were collected. RESULTS: 64.3% of study participants were women, mean age was 46.8 ± 11.0 years, and mean BMI was 34.2 ± 2.8 kg/m2. The completers analysis resulted in a weight loss of 3.2 ± 3.2 kg (3.2 ± 3.0%) in the ADHOC group and 0.4 ± 2.6 kg (0.3 ± 2.6%) in the EXPECT group after 12 weeks, with a significant difference between the groups (β [95% CI] = -2.9 [-3.8; -1.9], p < 0.001). Completers in the ADHOC group showed weight maintenance after 24 weeks. The time spent on the app was associated with weight reduction (β [95% CI] = -0.10 [-0.18; -0.01], p = 0.03). CONCLUSIONS: Application of a multimodal app-based weight loss program results in moderate weight loss in persons with obesity. TRIAL REGISTRATION: This study was registered in the German Clinical Trials Register (Registration number: DRKS00025291).
- Journal title abbreviation:
- Int J Obes (Lond)
- Year:
- 2024
- Journal volume:
- 48
- Journal issue:
- 1
- Pages contribution:
- 118-126
- Fulltext / DOI:
- doi:10.1038/s41366-023-01415-0
- Pubmed ID:
- http://view.ncbi.nlm.nih.gov/pubmed/38017117
- Print-ISSN:
- 0307-0565
- TUM Institution:
- Klinik für Ernährungsmedizin (Prof. Hauner)
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