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Titel:

Identification of allergenomic signatures in allergic and well-tolerated apple genotypes using LC-MS/MS

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Chebib, Soraya; Meng, Chen; Ludwig, Christina; Bergmann, Karl-Christian; Becker, Sylvia; Dierend, Werner; Schwab, Wilfried
Abstract:
The apple fruit (Malus domestica L. Borkh) is one of the most popular fruits worldwide. Beyond their beneficial properties, apples contain proteins that trigger allergic reactions in susceptible consumers. Mal d1 to d4 are allergens present in a variety of different isoforms in apples. In this study, we used proteomics to quantify all four Mal d proteins in 52 apple genotypes with varying allergenic potentials. A total of 195, 17, 14, and 18 peptides were found to be related to Mal d1, d2, d3, a...     »
Stichworte:
BayBioMS; Apple breeding; ELISA, Enzyme-Linked Immunosorbent Assay; GD, Golden Delicious; IgE, Immunoglobulin E; Isoforms; LC-MS/MS; LC-MS/MS, Liquid Chromatography tandem Mass Spectrometry; Mal d proteins; Malus domestica; OAS, Oral Allergy Syndrome; PR-10, Pathogenesis-Related protein 10; PSM, Peptide-Spectrum Match; Proteomics; SAN, Santana; nsLTP, non-specific Lipid Transfer Protein
Zeitschriftentitel:
Food Chemistry: Molecular Sciences
Jahr:
2022
Band / Volume:
4
Seitenangaben Beitrag:
100111
Volltext / DOI:
doi:10.1016/j.fochms.2022.100111
Verlag / Institution:
Elsevier BV
E-ISSN:
2666-5662
Publikationsdatum:
01.07.2022
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