Torlot, Lucien;Jarzab, Anna;Albert, Johanna;Pók-Udvari, Ágnes;Stahler, Arndt;Holch, Julian Walter;Gerlinger, Marco;Heinemann, Volker;Klauschen, Frederick;Kirchner, Thomas;Kumbrink, Jörg;Küster, Bernhard;Jung, Andreas
Proteomics uncover EPHA2 as a potential novel therapeutic target in colorectal cancer cell lines with acquired cetuximab resistance
Journal of Cancer Research and Clinical Oncology
2022
149
2
669-682

Stepan, Jens;Heinz, Daniel E.;Dethloff, Frederik;Bajaj, Thomas;Zellner, Andreas;Hafner, Kathrin;Wiechmann, Svenja;Mackert, Sarah;Mecdad, Yara;Rabenstein, Michael;Ebert, Tim;Martinelli, Silvia;Häusl, Alexander S.;Pöhlmann, Maximilian L.;Hermann, Anke;Ma, Xiao;Pavenstädt, Hermann;Schmidt, Mathias V.;Philipsen, Alexandra;Turck, Chris W.;Deussing, Jan M.;Kuster, Bernhard;Wehr, Michael C.;Stein, Valentin;Kremerskothen, Joachim;Wotjak, Carsten T.;Gassen, Nils C.
Hippo-released WWC1 facilitates AMPA receptor regulatory complexes for hippocampal learning
Cell Reports
2022
41
10
111766

Stumpf, M.;Ecker, V.;Giansanti, P.;Lu, J.;Zenz, T.;Ringshausen, I.;Küster, B.;Ruland, J.;Buchner, M.
P630: TARGETING NEGATIVE REGULATION OF MAPK SIGNALING IN CHRONIC LYMPHOCYTIC LEUKEMIA
HemaSphere
2022
6
528-529

Lier, Svenja;Sellmer, Andreas;Orben, Felix;Heinzlmeir, Stephanie;Krauß, Lukas;Schneeweis, Christian;Hassan, Zonera;Schneider, Carolin;Patricia Gloria Schäfer, Arlett;Pongratz, Herwig;Engleitner, Thomas;Öllinger, Rupert;Kuisl, Anna;Bassermann, Florian;Schlag, Christoph;Kong, Bo;Dove, Stefan;Kuster, Bernhard;Rad, Roland;Reichert, Maximilian;Wirth, Matthias;Saur, Dieter;Mahboobi, Siavosh;Schneider, Günter
A novel Cereblon E3 ligase modulator with antitumor activity in gastrointestinal cancer
Bioorganic Chemistry
2022
119
105505

Mergner, Julia;Kuster, Bernhard
Plant Proteome Dynamics
Annual Review of Plant Biology
2022
73
1
67-92

Falcomatà, Chiara;Bärthel, Stefanie;Widholz, Sebastian A.;Schneeweis, Christian;Montero, Juan José;Toska, Albulena;Mir, Jonas;Kaltenbacher, Thorsten;Heetmeyer, Jeannine;Swietlik, Jonathan J.;Cheng, Jing-Yuan;Teodorescu, Bianca;Reichert, Oliver;Schmitt, Constantin;Grabichler, Kathrin;Coluccio, Andrea;Boniolo, Fabio;Veltkamp, Christian;Zukowska, Magdalena;Vargas, Angelica Arenas;Paik, Woo Hyun;Jesinghaus, Moritz;Steiger, Katja;Maresch, Roman;Öllinger, Rupert;Ammon, Tim;Baranov, Olga;Robles, Maria S.;Rechenberger, Julia;Kuster, Bernhard;Meissner, Felix;Reichert, Maximilian;Flossdorf, Michael;Rad, Roland;Schmidt-Supprian, Marc;Schneider, Günter;Saur, Dieter
Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment
Nature Cancer
2022
3
3
318-336

Weiß, Lukas;Gaelings, Lana;Reiner, Tina;Mergner, Julia;Kuster, Bernhard;Fehér, Attila;Hensel, Götz;Gahrtz, Manfred;Kumlehn, Jochen;Engelhardt, Stefan;Hückelhoven, Ralph
Posttranslational modification of the RHO of plants protein RACB by phosphorylation and cross-kingdom conserved ubiquitination
PLOS ONE
2022
17
3
e0258924

Steimbach, Raphael R.;Herbst-Gervasoni, Corey J.;Lechner, Severin;Stewart, Tracy Murray;Klinke, Glynis;Ridinger, Johannes;Géraldy, Magalie N. E.;Tihanyi, Gergely;Foley, Jackson R.;Uhrig, Ulrike;Kuster, Bernhard;Poschet, Gernot;Casero, Robert A., Jr.;Médard, Guillaume;Oehme, Ina;Christianson, David W.;Gunkel, Nikolas;Miller, Aubry K.
Aza-SAHA Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout
Journal of the American Chemical Society
2022
144
41
18861-18875

Gabriel, Wassim;The, Matthew;Zolg, Daniel P.;Bayer, Florian P.;Shouman, Omar;Lautenbacher, Ludwig;Schnatbaum, Karsten;Zerweck, Johannes;Knaute, Tobias;Delanghe, Bernard;Huhmer, Andreas;Wenschuh, Holger;Reimer, Ulf;Médard, Guillaume;Kuster, Bernhard;Wilhelm, Mathias
Prosit-TMT: Deep Learning Boosts Identification of TMT-Labeled Peptides
Analytical Chemistry
2022
94
20
7181-7190

Orben, Felix;Lankes, Katharina;Schneeweis, Christian;Hassan, Zonera;Jakubowsky, Hannah;Krauß, Lukas;Boniolo, Fabio;Schneider, Carolin;Schäfer, Arlett;Murr, Janine;Schlag, Christoph;Kong, Bo;Öllinger, Rupert;Wang, Chengdong;Beyer, Georg;Mahajan, Ujjwal M.;Xue, Yonggan;Mayerle, Julia;Schmid, Roland M.;Kuster, Bernhard;Rad, Roland;Braun, Christian J.;Wirth, Matthias;Reichert, Maximilian;Saur, Dieter;Schneider, Günter
Epigenetic drug screening defines a PRMT5 inhibitor–sensitive pancreatic cancer subtype
JCI Insight
2022
7
10