A common atopy-associated variant in the TH2 cytokine locus control region impacts transcriptional regulation and alters SMAD3 and SP1 binding.
Autor(en):
Kretschmer, A. ; Möller, G. ; Lee, H.K. ; Laumen, H. ; von Toerne, C. ; Schramm, K. ; Prokisch, H. ; Eyerich, S. ; Wahl, S. ; Baurecht, H. ; Franke, A. ; Claussnitzer, M. ; Eyerich, K. ; Teumer, A. ; Milani, L. ; Klopp, N. ; Hauck, S.M. ; Illig, T. ; Peters, A. ; Waldenberger, M. ; Adamski, J. ; Reischl, E. ; Weidinger, S.
Stichworte:
Genetics and Epidemiology ; Enabling and Novel Technologies ; Allergy
Research Programmes: Genes and Environment in Common Diseases ; German Center for Diabetes Research ; Research Units: Institute of Epidemiology II (EPI2) ; Institute of Experimental Genetics (IEG) ; Institute of Human Genetics (IHG) ; Institute for Allergy Research (IAF) ; German Center for Diabetes Reseach (DZD) ; CCGs: Research Unit Protein Science (PROT)