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- Document type:
- Zeitschriftenaufsatz
- Author(s):
- Mueller, Kerstin; Michel, Klaus; Krueger, Dagmar; Demir, Ihsan Ekin; Ceyhan, Guralp Onur; Zeller, Florian; Kreis, Martin E.; Schemann, Michael
- Title:
- Activity of protease-activated receptors in the human submucous plexus.
- Abstract:
- BACKGROUND & AIMS: Protease-activated receptors (PARs) are expressed in the enteric nervous system. Excessive release of proteases has been reported in functional and inflammatory bowel diseases. Studies in several animal models indicate the involvement of neural PARs. We studied the actions of different
- Keywords:
- Calcium Signaling, Voltage-Sensitive Dye Imaging, Immunohistochemistry, Animals, Humans, Guinea Pigs, Female, Male, Middle Aged, Neurons/physiology, Neuroglia/physiology, Receptor, PAR-1/*metabolism, Receptor, PAR-2/*metabolism, Receptors, Thrombin/*metabolism, Submucous Plexus/*metabolism
- Journal title:
- Gastroenterology
- Year:
- 2011
- Journal volume:
- 141
- Month:
- dec
- Journal issue:
- 6
- Pages contribution:
- 2088--2097.e1
- Language:
- eng
- Fulltext / DOI:
- doi:10.1053/j.gastro.2011.08.034
- Print-ISSN:
- 1528-0012 0016-5085
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