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Document type:
Zeitschriftenaufsatz 
Author(s):
Mueller, Kerstin; Michel, Klaus; Krueger, Dagmar; Demir, Ihsan Ekin; Ceyhan, Guralp Onur; Zeller, Florian; Kreis, Martin E.; Schemann, Michael 
Title:
Activity of protease-activated receptors in the human submucous plexus. 
Abstract:
BACKGROUND & AIMS: Protease-activated receptors (PARs) are expressed in the enteric nervous system. Excessive release of proteases has been reported in functional and inflammatory bowel diseases. Studies in several animal models indicate the involvement of neural PARs. We studied the actions of different 
Keywords:
Calcium Signaling, Voltage-Sensitive Dye Imaging, Immunohistochemistry, Animals, Humans, Guinea Pigs, Female, Male, Middle Aged, Neurons/physiology, Neuroglia/physiology, Receptor, PAR-1/*metabolism, Receptor, PAR-2/*metabolism, Receptors, Thrombin/*metabolism, Submucous Plexus/*metabolism 
Journal title:
Gastroenterology 
Year:
2011 
Journal volume:
141 
Month:
dec 
Journal issue:
Pages contribution:
2088--2097.e1 
Language:
eng 
Print-ISSN:
1528-0012 0016-5085