Mueller, Kerstin; Michel, Klaus; Krueger, Dagmar; Demir, Ihsan Ekin; Ceyhan, Guralp Onur; Zeller, Florian; Kreis, Martin E.; Schemann, Michael
Activity of protease-activated receptors in the human submucous plexus.
BACKGROUND & AIMS: Protease-activated receptors (PARs) are expressed in the enteric nervous system. Excessive release of proteases has been reported in functional and inflammatory bowel diseases. Studies in several animal models indicate the involvement of neural PARs. We studied the actions of different