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Titel:

Time course of the anti-oedematous effect of O-(ss-Hydroxyethyl) rutosides in healthy volunteers

Autor(en):
Rehn, D.; Hennings, G.; Nocker, W.; Diebschlag, Wilfried
Abstract:
O-(beta-hydroxyethyl)-rutosides (HR) is used for the treatment of disorders of the venous and microcirculatory systems. In order to evaluate the time course of its activity, the effect of HR on a provocation model of orthostatic oedema in healthy volunteers was used. After a 2 week placebo run-in period, 16 healthy volunteers were randomized to HR (2 tablets of 500 mg/day) of placebo for a further 3 weeks, in a double-blind parallel design. Oedema was provoked by standing motionless for 1 h, wit...     »
Zeitschriftentitel:
Euro. J. Clin. Pharmacol.
Jahr:
1991
Band / Volume:
40
Heft / Issue:
6
Seitenangaben Beitrag:
625
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