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Titel:

P/Q-type and T-type calcium channels, but not type 3 transient receptor potential cation channels, are involved in inhibition of dendritic growth after chronic metabotropic glutamate receptor type 1 and protein kinase C activation in cerebellar Purkinje c

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Gugger, OS; Hartmann, J; Birnbaumer, L; Kapfhammer, JP
Abstract:
The development of a neuronal dendritic tree is modulated both by signals from afferent fibers and by an intrinsic program. We have previously shown that chronic activation of either type 1 metabotropic glutamate receptors (mGluR1s) or protein kinase C (PKC) in organotypic cerebellar slice cultures of mice and rats severely inhibits the growth and development of the Purkinje cell dendritic tree. The signaling events linking receptor activation to the regulation of dendritic growth remain largely...     »
Zeitschriftentitel:
Eur J Neurosci
Jahr:
2012
Band / Volume:
35
Heft / Issue:
1
Seitenangaben Beitrag:
20-33
Sprache:
eng
Volltext / DOI:
doi:10.1111/j.1460-9568.2011.07942.x
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/22188405
Print-ISSN:
0953-816X
TUM Einrichtung:
Institut für Neurowissenschaften
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