Prognostic impact of PD-1 and its ligands in renal cell carcinoma.

Title:: Prognostic impact of PD-1 and its ligands in renal cell carcinoma.
Document type:: Journal Article; Review; Review
Author(s):: Erlmeier, Franziska; Weichert, Wilko; Schrader, Andres Jan; Autenrieth, Michael; Hartmann, Arndt; Steffens, Sandra; Ivanyi, Philipp
Abstract:: Programmed death-1 receptor (PD-1) and programmed death-1 receptor-ligand (PD-L1) have been suggested to play a role as prognostic markers in clear cell renal cell carcinoma (ccRCC). The association between PD-L1 and prognosis seems to be more robust than for PD-1. Further, preliminary analyses suggest that neither PD-1 nor its ligands play a role as prognostic markers in non-clear cell RCC, while the prognostic role of PD-L2 in ccRCC as well as in non-clear cell RCC remains unclear.
Journal title abbreviation:: Med Oncol
Year:: 2017
Journal volume:: 34
Journal issue:: 6
Pages contribution:: 99
Language:: eng
Fulltext / DOI:: doi:10.1007/s12032-017-0961-y
Pubmed ID:: http://view.ncbi.nlm.nih.gov/pubmed/28432616
Print-ISSN:: 1357-0560
TUM Institution:: Institut für Allgemeine Pathologie und Pathologische Anatomie; Urologische Klinik und Poliklinik
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