Heart attack and stroke are the major causes of human death and atherosclerotic plaques
are the most common effect of cardiovascular disease. Intravascular ultrasound (IVUS),
a diagnostic imaging technique, offers a unique view of the morphology of the arterial
plaque displays the morphological and histological properties of a cross-section of the vessel. Limitations of the grayscale IVUS manual plaque assessment have led to the development of quantitative techniques for analysis of characteristics of plaque components.
In vivo plaque characterization with the so called Virtual Histology (VH)-IVUS is widely available for atherosclerosis plaque characterization in IVUS images. However, it suffers from a poor longitudinal resolution due to the ECG-gated acquisition. The focus of this PhD thesis is to provide effective methods for image-based vessel plaque characterization via IVUS image analysis
to overcome the limitations of current techniques. The proposed algorithms are also applicable
to the large amount of the IVUS image sequences obtained from patients in the past.
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Heart attack and stroke are the major causes of human death and atherosclerotic plaques
are the most common effect of cardiovascular disease. Intravascular ultrasound (IVUS),
a diagnostic imaging technique, offers a unique view of the morphology of the arterial
plaque displays the morphological and histological properties of a cross-section of the vessel. Limitations of the grayscale IVUS manual plaque assessment have led to the development of quantitative techniques for analysis of character...
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