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Title:

Meta-analysis of filaggrin polymorphisms in eczema and asthma: robust risk factors in atopic disease.

Document type:
Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Article
Author(s):
Rodriguez, E; Baurecht, H; Herberich, E; Wagenpfeil, S; Brown, SJ; Cordell, HJ; Irvine, AD; Weidinger, S
Abstract:
BACKGROUND: The discovery of filaggrin (FLG) null mutations as a major risk factor for eczema represents a milestone toward the understanding of an important mechanism in this complex disease. However, published studies demonstrate differences concerning design and effect size, and conflicting results for asthma have been reported. OBJECTIVES: We sought to provide a more accurate estimate of FLG effect sizes and to better refine FLG risk profiles within the broad and inclusive eczema diagnosis....     »
Journal title abbreviation:
J Allergy Clin Immunol
Year:
2009
Journal volume:
123
Journal issue:
6
Pages contribution:
1361-70.e7
Language:
eng
Fulltext / DOI:
doi:10.1016/j.jaci.2009.03.036
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/19501237
Print-ISSN:
0091-6749
TUM Institution:
Institut für Medizinische Statistik und Epidemiologie; Klinik und Poliklinik für Dermatologie und Allergologie; Molekulare Allergologie (Prof. Schmidt-Weber)
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