Häußler, Daniel;Manevski, Damjan;Frädrich, Julian;Brunner, Vanessa;Prokopchuk, Olga;Sommer, Alexander;Toledo, Batu;Knolle, Percy;Martignoni, Marc E;Friess, Helmut;Waterhouse, Paul;Krüger, Achim
Extent of N-glycosylation of the metalloproteinase inhibitor and cytokine TIMP-1 determines pancreatic cancer cell proliferation and survival via CD63.
J Biol Chem
2025
301
6

Miyara, Shoval;Adler, Miri;Umansky, Kfir B;Häußler, Daniel;Bassat, Elad;Divinsky, Yalin;Elkahal, Jacob;Kain, David;Lendengolts, Daria;Ramirez Flores, Ricardo O;Bueno-Levy, Hanna;Golani, Ofra;Shalit, Tali;Gershovits, Michael;Weizman, Eviatar;Genzelinakh, Alexander;Kimchi, Danielle M;Shakked, Avraham;Zhang, Lingling;Wang, Jingkui;Baehr, Andrea;Petrover, Zachary;Sarig, Rachel;Dorn, Tatjana;Moretti, Alessandra;Saez-Rodriguez, Julio;Kupatt, Christian;Tanaka, Elly M;Medzhitov, Ruslan;Krüger, Achim;Mayo, Avi;Alon, Uri;Tzahor, Eldad
Cold and hot fibrosis define clinically distinct cardiac pathologies.
Cell Syst
2025
16
3

Ren, Lei;Liu, Chunfeng;Çifcibaşı, Kaan;Ballmann, Markus;Rammes, Gerhard;Mota Reyes, Carmen;Tokalov, Sergey;Klingl, Andreas;Grünert, Jennifer;Goyal, Keshav;Neckel, Peter H;Mattheus, Ulrich;Schoeps, Benjamin;Yıldızhan, Saliha Elif;Sezerman, Osman Ugur;Cevik, Nedim Can;Sever, Elif Arik;Karakas, Didem;Safak, Okan;Steiger, Katja;Muckenhuber, Alexander;Görgülü, Kıvanç;Chen, Zongyao;Zhang, JingCheng;Ye, Linhan;Maula Ali, Mohammed Inayatullah;Tiwari, Vijay K;Romanyuk, Nataliya;Giesert, Florian;Saur, Dieter;Rad, Roland;Schmid, Roland M;Algül, Hana;Krüger, Achim;Friess, Helmut;Ceyhan, Güralp O;Istvanffy, Rouzanna;Demir, Ihsan Ekin
Sensory neurons drive pancreatic cancer progression through glutamatergic neuron-cancer pseudo-synapses.
Cancer Cell
2025
43
12
2241-2258.e8

Bernaerts, Eline;Ahmadzadeh, Kourosh;De Visscher, Amber;Malengier-Devlies, Bert;Häuβler, Daniel;Mitera, Tania;Martens, Erik;Krüger, Achim;De Somer, Lien;Matthys, Patrick;Vandooren, Jennifer
Human monocyte-derived macrophages shift subcellular metalloprotease activity depending on their activation state.
iScience
2024
27
11

Lambert, Jordi;Oc, Sebnem;Worssam, Matthew D;Häußler, Daniel;Solomon, Charles U;Figg, Nichola L;Baxter, Ruby;Imaz, Maria;Taylor, James C K;Foote, Kirsty;Finigan, Alison;Mahbubani, Krishnaa T;Webb, Tom R;Ye, Shu;Bennett, Martin R;Krüger, Achim;Spivakov, Mikhail;Jørgensen, Helle F
Network-based prioritization and validation of regulators of vascular smooth muscle cell proliferation in disease.
Nat Cardiovasc Res
2024
3
6
714-733

Wang, Xiaobo;Istvanffy, Rouzanna;Ye, Linhan;Teller, Steffen;Laschinger, Melanie;Diakopoulos, Kalliope N;Görgülü, Kıvanç;Li, Qiaolin;Ren, Lei;Jäger, Carsten;Steiger, Katja;Muckenhuber, Alexander;Vilne, Baiba;Çifcibaşı, Kaan;Mota Reyes, Carmen;Yurteri, Ümmügülsüm;Kießler, Maximilian;Gürçınar, Ibrahim H;Sugden, Maya M;Yıldızhan, Saliha Elif;Sezerman, Osman Ugur;Çilingir, Sümeyye;Süyen, Güldal;Reichert, Maximilian;Schmid, Roland M;Bärthel, Stefanie;Öllinger, Rupert;Krüger, Achim;Rad, Roland;Saur, Dieter;Algül, Hana;Friess, Helmut;Lesina, Marina;Ceyhan, Güralp Onur;Demir, Ihsan Ekin
Phenotype screens of murine pancreatic cancer identify a Tgf-α-Ccl2-paxillin axis driving human-like neural invasion.
J Clin Invest
2023
133
21

Bayerl, Felix;Meiser, Philippa;Donakonda, Sainitin;Hirschberger, Anna;Lacher, Sebastian B;Pedde, Anna-Marie;Hermann, Chris D;Elewaut, Anais;Knolle, Moritz;Ramsauer, Lukas;Rudolph, Thomas J;Grassmann, Simon;Öllinger, Rupert;Kirchhammer, Nicole;Trefny, Marcel;Anton, Martina;Wohlleber, Dirk;Höchst, Bastian;Zaremba, Anne;Krüger, Achim;Rad, Roland;Obenauf, Anna C;Schadendorf, Dirk;Zippelius, Alfred;Buchholz, Veit R;Schraml, Barbara U;Böttcher, Jan P
Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses.
Immunity
2023
56
6
1341-1358.e11

Malehmir, Mohsen;Pfister, Dominik;Gallage, Suchira;Szydlowska, Marta;Inverso, Donato;Kotsiliti, Elena;Leone, Valentina;Peiseler, Moritz;Surewaard, Bas G J;Rath, Dominik;Ali, Adnan;Wolf, Monika Julia;Drescher, Hannah;Healy, Marc E;Dauch, Daniel;Kroy, Daniela;Krenkel, Oliver;Kohlhepp, Marlene;Engleitner, Thomas;Olkus, Alexander;Sijmonsma, Tjeerd;Volz, Julia;Deppermann, Carsten;Stegner, David;Helbling, Patrick;Nombela-Arrieta, César;Rafiei, Anahita;Hinterleitner, Martina;Rall, Marcel;Baku, Florian;Borst, Oliver;Wilson, Caroline L;Leslie, Jack;O'Connor, Tracy;Weston, Christopher J;Chauhan, Abhishek;Adams, David H;Sheriff, Lozan;Teijeiro, Ana;Prinz, Marco;Bogeska, Ruzhica;Anstee, Natasha;Bongers, Malte N;Notohamiprodjo, Mike;Geisler, Tobias;Withers, Dominic J;Ware, Jerry;Mann, Derek A;Augustin, Hellmut G;Vegiopoulos, Alexandros;Milsom, Michael D;Rose, Adam J;Lalor, Patricia F;Llovet, Josep M;Pinyol, Roser;Tacke, Frank;Rad, Roland;Matter, Matthias;Djouder, Nabil;Kubes, Paul;Knolle, Percy A;Unger, Kristian;Zender, Lars;Nieswandt, Bernhard;Gawaz, Meinrad;Weber, Achim;Heikenwalder, Mathias
Author Correction: Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer.
Nat Med
2022
28
3

Bolik, Julia;Krause, Freia;Stevanovic, Marija;Gandraß, Monja;Thomsen, Ilka;Schacht, Sarah-Sophie;Rieser, Eva;Müller, Miryam;Schumacher, Neele;Fritsch, Jürgen;Wichert, Rielana;Galun, Eithan;Bergmann, Juri;Röder, Christian;Schafmayer, Clemens;Egberts, Jan-Hendrik;Becker-Pauly, Christoph;Saftig, Paul;Lucius, Ralph;Schneider-Brachert, Wulf;Barikbin, Roja;Adam, Dieter;Voss, Matthias;Hitzl, Wolfgang;Krüger, Achim;Strilic, Boris;Sagi, Irit;Walczak, Henning;Rose-John, Stefan;Schmidt-Arras, Dirk
Inhibition of ADAM17 impairs endothelial cell necroptosis and blocks metastasis.
J Exp Med
2022
219
1

Schoeps, Benjamin;Frädrich, Julian;Krüger, Achim
Cut loose TIMP-1: an emerging cytokine in inflammation.
Trends Cell Biol
2023
33
5
413-426