Self-expanding metal stents versus polyethylene stents for palliative treatment in patients with advanced pancreatic cancer.

Weber, A; Mittermeyer, T; Wagenpfeil, S; Schmid, RM; Prinz, C

doi:10.1097/MPA.0b013e3181870ab8

journal article

Titel:: Self-expanding metal stents versus polyethylene stents for palliative treatment in patients with advanced pancreatic cancer.
Dokumenttyp:: Journal Article
Autor(en):: Weber, A; Mittermeyer, T; Wagenpfeil, S; Schmid, RM; Prinz, C
Abstract:: OBJECTIVES: Endoscopic biliary drainage is widely accepted as palliative treatment in patients with pancreatic cancer. The current study was designed to compare self-expanding metal stent and polyethylene stent in a homogeneous patient group with advanced pancreatic cancer. METHODS: The study included 154 patients initially treated with a metal or plastic stent. Median survival time, stent patency, and stent-associated hospital admissions were evaluated. RESULTS: The median survival time in patients treated with metal and plastic stent was 5.9 and 4.4 months (P = 0.074), respectively. Self-expanding metal stents have a significantly higher patency rate than polyethylene stents. Stent occlusion was observed in 21 (33%) of 63 patients in the plastic stent group after a median period of 57 days and in 17 (19%) of 91 patients in the metal stent group after a median period of 126 days. The total time of hospital stay after initial implantation of metal or plastic stent was 7 and 16.5 days, respectively (P < 0.001). CONCLUSIONS: Self-expanding metal stents have a longer patency than polyethylene stents. Additionally, the number of stent-associated hospital admissions and the total time of hospital stay were higher in the plastic stent group. The median survival time was not significantly different in both groups.
Zeitschriftentitel:: Pancreas
Jahr:: 2009
Band / Volume:: 38
Heft / Issue:: 1
Seitenangaben Beitrag:: e7-e12
Sprache:: eng
Volltext / DOI:: doi:10.1097/MPA.0b013e3181870ab8
PubMed:: http://view.ncbi.nlm.nih.gov/pubmed/18766117
Print-ISSN:: 0885-3177
TUM Einrichtung:: II. Medizinische Klinik und Poliklinik (Gastroenterologie); Institut für Medizinische Statistik und Epidemiologie
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