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Titel:

Driver or coincidence detector: modal switch of a corticothalamic giant synapse controlled by spontaneous activity and short-term depression.

Dokumenttyp:
In Vitro; Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Groh, A; de Kock, CP; Wimmer, VC; Sakmann, B; Kuner, T
Abstract:
Giant synapses between layer 5B (L5B) neurons of somatosensory (barrel) cortex and neurons of the posteromedial nucleus (POm) of thalamus reside in a key position of the cortico-thalamo-cortical (CTC) loop, yet their synaptic properties and contribution to CTC information processing remain poorly understood. Fluorescence-guided local stimulation of terminals were combined with postsynaptic whole-cell recordings in thalamus to study synaptic transmission at an identified giant synapse. We found l...     »
Zeitschriftentitel:
J Neurosci
Jahr:
2008
Band / Volume:
28
Heft / Issue:
39
Seitenangaben Beitrag:
9652-63
Sprache:
eng
Volltext / DOI:
doi:10.1523/JNEUROSCI.1554-08.2008
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/18815251
Print-ISSN:
0270-6474
TUM Einrichtung:
Institut für Neurowissenschaften
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