The subject of this thesis is the realization and characterization of field-effect sensors based on group III-nitrides (GaN, AlGaN) for electrochemical and biochemical analytics. The electrochemical properties of the interface of AlGaN to aqueous electrolytes as well as their organic functionalization by lipid membranes or alkylsilane monolayers was investigated by electrochemical impedance spectroscopy and cyclic voltammetry. For the extracellular measurement of electrophysiological cell signals, solution-gate field-effect transistor arrays based on AlGaN/GaN heterostructures have been realized and their low frequency noise was analyzed. Heart cells of embryonic rats were cultivated directly on the gate surface, and their spontaneous action potentials were recorded via corresponding changes of the transistor channel current.
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The subject of this thesis is the realization and characterization of field-effect sensors based on group III-nitrides (GaN, AlGaN) for electrochemical and biochemical analytics. The electrochemical properties of the interface of AlGaN to aqueous electrolytes as well as their organic functionalization by lipid membranes or alkylsilane monolayers was investigated by electrochemical impedance spectroscopy and cyclic voltammetry. For the extracellular measurement of electrophysiological cell signal...
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