Obesity causes not only many health problems, but also may influence postoperative outcomes after tumor surgery. As bladder cancer is the ninth most frequent malignant tumor worldwide, it is also of interest to analyze the impact of patients´ body mass index (BMI) on the outcome after radical sugery because of bladder cancer.
In our study, the overweight and obese patients did not exhibit more pre-operative symptoms, higher tumor staging after transuretheral resection and after radical cystectomy or an increased rate of complications. Surgical time and volume of blood transfusions (among ileal neobladder recipients) were increased with higher BMI, but again without significance. Upon exclusion of underweight patients, a significant increase of survival for overweight patients after radical cystectomy could be demonstrated. Furthermore, survival probability significantly correlated to the type of urinary diversion chosen. No significant associations, among our patients, were seen between BMI and tumor specific survival, rate of local tumor recurrence, tumor progression or metastasis.
Even though many studies have shown that obesity considerably increases risk of cancer development and decreases the survival probability of cancer patients, in our study high BMI did not significantly affect survival outcomes of patients who underwent radical cystectomy for bladder cancer. Therefore, elevated body mass indices should not per se be a prominent factor in deciding against radical cystectomy for bladder cancer.
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Obesity causes not only many health problems, but also may influence postoperative outcomes after tumor surgery. As bladder cancer is the ninth most frequent malignant tumor worldwide, it is also of interest to analyze the impact of patients´ body mass index (BMI) on the outcome after radical sugery because of bladder cancer.
In our study, the overweight and obese patients did not exhibit more pre-operative symptoms, higher tumor staging after transuretheral resection and after radical cystecto...
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