In this work techniques were developed using colloidal particles to study the dynamics of single polymers in biopolymer-networks. In order to determine local viscoelastic properties on a micrometer length scales, nano-scale particles were coupled to single test-polymers of actin-networks and surface-grafted films of hyaluronic acid. The analysation of the thermally driven or externally induced particle motion, by application of the magnetic tweezers technique, provided direct insight to aspects of molecular interaction processes and their connection to macroscopic viscoelastic properties of the studied systems.
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In this work techniques were developed using colloidal particles to study the dynamics of single polymers in biopolymer-networks. In order to determine local viscoelastic properties on a micrometer length scales, nano-scale particles were coupled to single test-polymers of actin-networks and surface-grafted films of hyaluronic acid. The analysation of the thermally driven or externally induced particle motion, by application of the magnetic tweezers technique, provided direct insight to aspects...
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